上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2019, Vol. 39 ›› Issue (12): 1427-.doi: 10.3969/j.issn.1674-8115.2019.12.014

• 论著·临床研究 • 上一篇    下一篇

初步探讨颈动脉黏弹性与血流剪切率的相关性

杨兴益1，罗向红2，邵思惠3，杜联芳3，李朝军3   

  1. 1. 山西医科大学汾阳学院，汾阳 032200；2. 上海交通大学附属第一人民医院心动图室，上海 200080；3. 上海交通大学附属第一人民医院超声医学科，上海 200080
  • 出版日期:2019-12-28 发布日期:2020-02-06
  • 通讯作者: 李朝军，电子信箱：lzj_1975@sina.com。
  • 作者简介:杨兴益（1970—），男，副教授，硕士；电子信箱：yxyybw@163.com。
  • 基金资助:
    上海市科学技术委员会医学引导类科技支撑项目（16411969300）；上海市卫生和计划生育委员会基金（201640043）；促进市级医院临床技能与临床创新能力三年行动计划（16CR3105B）；上海交通大学“医工交叉基金”（YG2015MS28）；上海市松江区科技攻关项目（18sjkjgg72，18sjkjgg53）

Preliminary study on correlation between carotid viscoelasticity and blood flow shear rate

YANG Xing-yi, LUO Xiang-hong, SHAO Si-hui, DU Lian-fang, LI Zhao-jun   

  1. 1. Fenyang College of Shanxi Medical University, Fenyang 032200, China; 2. Department of Echocardiography, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; 3. Department of Ultrasound Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China
  • Online:2019-12-28 Published:2020-02-06
  • Supported by:
    Medical Guidance Science and Technology Support Project of Shanghai Science and Technology Committee, 16411969300; Shanghai Health and Family Planning Commission Fund, 201640043; Three-year Plan for Clinical Skills and Innovation in Municipal Hospitals, 16CR3105B; Interdisciplinary Program of Shanghai Jiao Tong University, YG2015MS28; Shanghai Songjiang District Science and Technology Project, 18sjkjgg72, 18sjkjgg53

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摘要： 目的·应用超声剪切波频散（ultrasonic shear wave dispersion，USWD）技术检测颈动脉黏弹性，初步探讨其与血流剪切率的相关性。方法·招募2018年12月—2019年1月于上海交通大学附属第一人民医院普外科住院的患者45例，依据年龄中位数将其分为高年龄组（≥50岁）和低年龄组（R）和剪切波频散（shear wave dispersion，SWDR），以及其血流最大剪切率（maximum shear rate，SRmax）和平均剪切率（mean shear rate，SRmean）。采用Pearson相关分析评估SWER和SWDR与血流剪切率的相关性。结果·①与低年龄组比较，高年龄组患者颈动脉SWER、SWDR、SRmax和SRmean均较低（均PR和黏性指标SWDR分别与SRmax和SRmean呈正相关（均P结论·基于USWD技术的颈动脉黏弹性指标与血流剪切率密切相关，其有望为颈动脉疾病的研究提供新的视角。

关键词: 超声剪切波频散, 颈动脉, 剪切率, 黏弹性

Abstract:

Objective · To examine the carotid viscoelasticityusing ultrasonic shear wave dispersion (USWD) technique, and to preliminarily analyze its correlation with blood flow shear rate. Methods · Forty-five patients of General Surgery Department of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine December 2018 to January 2019 were recruited, and divided into the elder group ( ≥ 50 years old) and the younger group (R), shear wave dispersion (SWDR), blood flow maximum shear rate (SRmax) and mean shear rate (SRmean). The correlations between SWER, SWDR and blood flow shear rate were analyzedPearson correlation, respectively. Results · ①Compared with the younger group, the carotid artery SWER, SWDR, SRmax and SRmean of the patients in the elder group were lower (all PR and SWDR of carotid artery of all patients were positively correlated with SRmax and SRmean, respectively (all PConclusion · Carotid arterial viscoelastic index based on USWD technique is closely related to the blood flow shear rate, which is expected to provide a new perspective for the study of carotid arterial diseases.

Key words: ultrasonic shear wave dispersion (USWD), carotid artery, shear rate, viscoelasticity