上海交通大学学报(医学版) ›› 2021, Vol. 41 ›› Issue (1): 108-111.doi: 10.3969/j.issn.1674-8115.2021.01.020

• 综述 • 上一篇    下一篇

围术期微循环的相关研究进展

阎乃璐(), 陆菡(), 于布为()   

  1. 上海交通大学医学院附属瑞金医院麻醉科,上海 200025
  • 出版日期:2021-01-28 发布日期:2021-02-22
  • 通讯作者: 于布为 E-mail:1123278238@qq.com;yubuwei_2013@126.com
  • 作者简介:阎乃璐(1992—),女,硕士生;电子信箱:1123278238@qq.com|阎乃璐(1992—),女,硕士生;电子信箱:1123278238@qq.com
  • 基金资助:
    国家自然科学基金(81771138)

Research progress in perioperative microcirculation

Nai-lu YAN(), Han LU(), Bu-wei YU()   

  1. Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Online:2021-01-28 Published:2021-02-22
  • Contact: Bu-wei YU E-mail:1123278238@qq.com;yubuwei_2013@126.com
  • Supported by:
    Funding Information] National Natural Science Foundation of China(81771138)

摘要:

随着科学技术的发展,从机体微循环角度出发进行围术期管理受到越来越多的关注。麻醉状态下受麻醉药物、非麻醉药物、手术和液体治疗等因素的影响,机体可产生微循环紊乱。各因素中,液体治疗对微循环的改善作用获得较多认可。麻醉领域、重症领域研究者均曾提出以微循环为导向的液体治疗或复苏理念,但缺少大量临床研究的证实。目前,旁流暗视野技术可实现机体微循环的床旁、无创、实时的监测,可安全地应用于临床,借以实时观察微循环状态,调整液体类型、输注速度及液体总量以改善微循环,改善患者预后。以微循环为导向的液体治疗无疑将成为未来麻醉管理的一个重要方向。文章就围术期微循环的相关研究进展作一综述。

关键词: 微循环, 围术期, 麻醉, 液体治疗

Abstract:

With the development of science and technology, more and more attention has been paid to perioperative microcirculation management. In anesthesia, with the influence of anesthetics, non-anesthetic drugs, surgery, fluid therapy and other factors, microcirculation disorder exists in humans. The benefits of fluid therapy for microcirculation have been more popular than other factors. Anesthesiologists or experts in intensive medical all have ever put forward the concept of microcirculation-oriented fluid therapy or fluid resuscitation, which lacks a large number of clinical studies. At present, the sidestream dark field technology can realize the bedside, non-invasive and real-time monitoring of body microcirculation, and it safely comes into practice in clinical background. It helps monitor the state of microcirculation timely, and thus it's believed that the microcirculation and prognosis of patients can be improved by adjusting the category of fluid and controlling the infusion speed and fluid volume. Microcirculation-oriented fluid therapy will undoubtedly become an important direction of anesthesia management in the future. This article reviews the relative research progress in perioperative microcirculation.

Key words: microcirculation, perioperative period, anaesthesia, fluid therapy

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