上海交通大学学报（医学版）

上海交通大学学报(医学版) ›› 2021, Vol. 41 ›› Issue (1): 95-98.doi: 10.3969/j.issn.1674-8115.2021.01.017

• 综述 • 上一篇    下一篇

经颅聚焦超声刺激治疗精神障碍的研究现状及展望

翟兆琳(), 刘登堂()   

  1. 上海交通大学医学院附属精神卫生中心早期精神病性障碍科，上海 200030
  • 出版日期:2021-01-28 发布日期:2021-02-22
  • 作者简介:翟兆琳（1995—），女，硕士生；电子信箱：tvxqzhaizhaolin@126.com。
  • 基金资助:
    国家自然科学基金(81371479);上海市精神卫生中心临床研究中心重点项目(CRC2017ZD03);上海市精神卫生中心早期精神病性障碍亚专科项目(2013-YJTSZK-05)

Research status and prospect of transcranial focused ultrasound stimulation in treatment of psychiatric disorders

Zhao-lin ZHAI(), Deng-tang LIU()   

  1. Division of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2021-01-28 Published:2021-02-22
  • Supported by:
    Funding Information] National Natural Science Foundation of China(81371479);Key Program of SMHC Clinical Research Center(CRC2017ZD03);Early Psychosis Program of Shanghai Mental Health Center(2013-YJTSZK-05)

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摘要：

经颅聚焦超声刺激作为一种非侵入性的大脑调控技术，具有无创安全、聚焦区域精准、穿透部位深、易兼容神经影像同步记录的优势。经颅聚焦超声刺激已在治疗特发性震颤、帕金森病、脑肿瘤等疾病中得到应用，但在精神科领域仍发展缓慢。该文对经颅聚焦超声刺激治疗精神障碍的研究现状进行综述，分析目前该技术应用所面临的困境，并对未来做出展望。

关键词: 经颅聚焦超声刺激, 物理治疗, 神经调控, 精神障碍

Abstract:

As a non-invasive neuromodulation technique, transcranial focused ultrasound stimulation has the advantages of safety, high focused accuracy, deep penetration depth and easy compatibility with the synchronous recording of neuroimaging. Transcranial focused ultrasound stimulation has been used in the treatment of essential tremor, Parkinson's disease, brain tumors, etc. However, the progress in the area of psychiatry is still limited. The current research status of transcranial focused ultrasound stimulation in the treatment of psychiatric disorders is reviewed in this article, including the analysis of difficulties in its application and the prospect for the future direction.

Key words: transcranial focused ultrasound stimulation (tFUS), physiotherapy, neuromodulation, psychiatric disorders

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