上海交通大学学报（医学版）

上海交通大学学报(医学版) ›› 2021, Vol. 41 ›› Issue (1): 99-102.doi: 10.3969/j.issn.1674-8115.2021.01.018

• 综述 • 上一篇    下一篇

镇静催眠药物滥用及干预方式的研究进展

叶玉剑(), 钟娜, 赵敏()   

  1. 上海交通大学医学院附属精神卫生中心物质依赖科，上海 200030
  • 出版日期:2021-01-28 发布日期:2021-02-22
  • 通讯作者: 赵敏 E-mail:yeyujian1995@163.com;drminzhao@smhc.org.cn
  • 作者简介:叶玉剑（1995—），男，硕士生；电子信箱：yeyujian1995@163.com。
  • 基金资助:
    国家自然科学基金(81771436);上海市优秀学术带头人计划(17XD1403300);上海市科技重大专项(2018SHZDZX05);上海市精神卫生中心临床研究中心重大研究计划(CRC2018YB02)

Research progress of sedative-hypnotics abuse and the interventions

Yu-jian YE(), Na ZHONG, Min ZHAO()   

  1. Department of Drug Dependence, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2021-01-28 Published:2021-02-22
  • Contact: Min ZHAO E-mail:yeyujian1995@163.com;drminzhao@smhc.org.cn
  • Supported by:
    Funding Information] National Natural Science Foundation of China(81771436);Shanghai Outstanding Academic Leaders Plan(17XD1403300);Shanghai Municipal Science and Technology Major Project(2018SHZDZX05);Significant Research Plan of Research Center of Shanghai Mental Health Center(CRC2018YB02)

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摘要：

镇静催眠药物具有起效快速、疗效可靠、安全性高的特点，已经成为失眠、焦虑、癫痫以及酒精依赖戒断治疗的一线用药。合理使用此类药物具有重要的临床应用价值，但滥用或不当使用可能会造成患者记忆下降、意外伤害风险增加等不良后果。已有一些针对患者或处方医师的干预研究，旨在降低镇静催眠药滥用或不当使用的风险。该文就镇静催眠药物滥用的现状及干预方式进行综述，以期为合理应用镇静催眠药及后续相关研究提供依据。

关键词: 镇静催眠药物, 药物滥用, 干预方式

Abstract:

For the fast-action, reliable efficacy and high safety, sedative-hypnotics have become the first-line drugs for insomnia, anxiety, epileptic seizure and alcohol-dependence withdrawal treatment. Rational use of such drugs has important application value in clinic. However, abuse or misuse might lead to adverse consequences such as memory impairment and increased risk of accidental injury. There have been some studies aiming at patients or prescribers to reduce the risk of overuse of sedative-hypnotics. This article reviews the prevalence of sedative-hypnotics abuse and corresponding interventions, with a view to providing the evidence of rational application as well as the basis for the subsequent researches on sedative-hypnotics.

Key words: sedative-hypnotics, drug abuse, intervention

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