上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (1): 115-.doi: 10.3969/j.issn.1674-8115.2011.01.027

• 短篇论著 • 上一篇    下一篇

脱细胞异体真皮基质生物补片修补新生儿及婴幼儿组织缺损

王丽亚, 董彦清, 张鹏举, 宫颖新, 刘 锋   

  1. 河北省儿童医院普外科, 石家庄 050000
  • 出版日期:2011-01-28 发布日期:2011-02-01
  • 作者简介:王丽亚（1957—）, 女, 主任医师, 硕士；电子信箱: wly613@263.net。

Allogenous acellular dermal matrix biomaterial patches in the repair of tissue defects

WANG Li-ya, DONG Yan-qing, ZHANG Peng-ju, GONG Ying-xin, LIU Feng   

  1. Department of General Surgery, The Children's Hospital of Hebei Province, Shijiazhuang 050000, China
  • Online:2011-01-28 Published:2011-02-01

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摘要：

目的 观察脱细胞异体真皮基质生物补片修补新生儿和婴幼儿不同类型及部位组织缺损的效果。方法 采用脱细胞异体真皮基质生物补片修补新生儿和婴幼儿组织缺损，其中巨型脐膨出患儿膨出物切除后的腹壁缺损3例、腹壁神经纤维瘤切除后的腹壁缺损 1例、直肠阴道瘘1例、坏死性筋膜炎致臀部皮下组织及皮肤坏死1例。结果 除1例巨型脐膨出患儿家长放弃治疗外，其余患儿恢复良好，无并发症发生。结论 脱细胞异体真皮基质生物补片修补新生儿及婴幼儿不同部位组织缺损的效果良好。

关键词: 脱细胞异体真皮基质, 组织缺损, 手术, 婴幼儿, 新生儿

Abstract:

Objective To investigate the application of allogenous acellular dermal matrix biomaterial patches in the repair of tissue defects of different types and positions in neonates and infants. Methods Allogenous acellular dermal matrix biomaterial patches were used in the repair of tissue defects of different types and positions in neonates and infants. There were 3 patients with abdominal wall defect after bulge excision for giant hilum, 1 patient with abdominal wall defect after abdominal fibroma excision, 1 patient with rectovaginal fistula and 1 patient with coxal skin necrosis caused by necrotizing fasciitis. Results One patient with giant hilum resigned from treatment, and the other 5 patients gained favorable recovery, with no complications. Conclusion Allogenous acellular dermal matrix biomaterial patches may yield good outcomes in the repair of tissue defects of different types and positions in neonates and infants.

Key words: acellular dermal matrix, tissue defect, surgery, newborn, infant