上海交通大学学报（医学版）

›› 2011, Vol. 31 ›› Issue (2): 198-.doi: 10.3969/j.issn.1674-8115.2011.02.018

• 论著（临床研究） • 上一篇    下一篇

儿童代谢综合征影响因素的病例-对照研究

丁慧萍, 丁 倩, 张福东, 王 涛, 蔡美琴   

  1. 上海交通大学 医学院营养系, 上海 200025
  • 出版日期:2011-02-28 发布日期:2011-03-01
  • 通讯作者: 蔡美琴, 电子信箱: caimeiqin9@yahoo.com.cn。
  • 作者简介:丁慧萍（1984—）, 女, 硕士生；电子信箱: kailisu1984@yahoo.cn。
  • 基金资助:

    达能营养中心膳食营养研究与宣教基金（DIC2008）

Case-control study on influencing factors of metabolic syndrome in children

DING Hui-ping, DING Qian, ZHANG Fu-dong, WANG Tao, CAI Mei-qin   

  1. Department of Nutrition, Shanghai Jiaotong University, Shanghai 200025, China
  • Online:2011-02-28 Published:2011-03-01
  • Supported by:

    Danone Institute Foundation, DIC2008

PDF (PC)

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摘要：

目的 了解正常体质量、超重和肥胖儿童中代谢综合征（MS）及其各组分的检出情况，并分析家庭因素、饮食行为及膳食因素与儿童MS之间的关系。方法 选择上海市卢湾区和宝山区各1所小学1 707名儿童，筛查出超重和肥胖儿童364名，将其中同意抽取静脉血的94名儿童根据筛查结果进一步分为超重组（n=34）和肥胖组（n=60）；同时设立正常体质量的对照组（n=120）。采用病例-对照研究方法，通过问卷调查、体格测量、血压和血液生化检测，分析MS发生的相关影响因素。结果 1 707名儿童的超重率和肥胖率分别为12.8%和9.1%；男生超重率和肥胖率均明显高于女生（P=0.000）；卢湾区小学儿童超重率和肥胖率明显高于宝山区（P=0.000）。采用Cook诊断标准，发现MS发病率在对照组、超重组、肥胖组中分别为0.8%、2.9%和6.7%。肥胖组儿童中，腹型肥胖、高血压、高三酰甘油（TG）血症和低高密度脂蛋白胆固醇（HDL-C）血症的总检出率分别为76.7％、46.7％、11.7％和6.7％，具有l、2和3项MS组分者分别占51.7％、35.0％和6.7％。多因素Logistic回归分析显示：蛋白质、钙、维生素C、维生素E的摄入量高是MS各组分的保护因素，父母肥胖、食量大、进食速度快、祖父母为其烹饪、父母对其饮食行为的影响是MS各组分的危险因素。结论 被调查儿童的MS发病率较高；家庭因素、饮食习惯及膳食因素与MS各组分的发生有密切关系。

关键词: 儿童, 肥胖, 代谢综合征, 影响因素

Abstract:

Objective To investigate the prevalences of metabolic syndrome (MS) and MS components in children with normal weight, overweight and obesity, and to explore the relationship between MS and family factors, eating behaviors and diet factors. Methods A total of 1 707 children from one primary school of Luwan District and one primary school of Baoshan District in Shanghai were selected, and 364 children with overweight and obesity were screened. Ninety-four venous blood samples were available from these 364 children, and overweight group (n=34) and obesity group (n=60) were divided. Besides, control group of children with normal weight was established (n=120). With case-control method, the influencing factors of MS were analysed by questionnaire survey, physical examinations, blood pressure and blood biochemical marker measurement. Results The prevalences of overweight and obesity in 1 707 children were 12.8% and 9.1%, respectively. Both the overweight rate and obesity rate in boys were significantly higher than those in girls (P=0.000). Both the overweight rate and obesity rate of children in Luwan District were significantly higher than those of children in Baoshan District (P=0.000). By Cook diagnostic criteria, the prevalences of MS in control group, overweight group and obesity group were 0.8%, 2.9% and 6.7%, respectively. In children of obesity group, the prevalences of abdominal obesity, hypertension, high triglyceride and low high density lipoprotein-cholesterol were 76.7％, 46.7％, 11.7％ and 6.7％, respectively, and those with one, two and three MS components accounted for 51.7%, 35.0% and 6.7%, respectively. Multivariate analysis revealed that protein, calcium, vitamin C and vitamin E were protective factors of MS components, while parental obesity, taking food too fast, big appetite and cooking by grandparents were risk factors of MS components. Conclusion The prevalence of MS is high among investigated children. Family factors, eating behaviors and diet factors are related to MS components.

Key words: child, obesity, metabolic syndrome, influencing factor