上海交通大学学报（医学版）

›› 2012, Vol. 32 ›› Issue (8): 1088-.doi: 10.3969/j.issn.1674-8115.2012.08.027

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以肿瘤分子标志物为基础的转化医学研究进展

李建芳, 朱正纲, 刘炳亚   

  1. 上海交通大学 医学院附属瑞金医院外科 |上海消化外科研究所 |上海市胃肿瘤重点实验室, 上海 200025
  • 出版日期:2012-08-28 发布日期:2012-08-29
  • 通讯作者: 刘炳亚, 电子信箱: byliu@sjtu.edu.cn。
  • 作者简介:李建芳（1974—）, 女, 主管技师；电子信箱: rjljf@yahoo.com.cn。

Research progress of translational medicine based on tumor molecular biomarkers

LI Jian-fang, ZHU Zheng-gang, LIU Bing-ya   

  1. Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2012-08-28 Published:2012-08-29

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摘要：

近年来，随着分子生物学等基础医学研究的快速发展和医学模式的转变，诞生了转化医学的概念。转化医学是将医学生物学基础研究成果迅速、有效地转化为可在临床实际中应用的理论、技术、方法和药物，在实验室与病房（bench to bedside）之间架起相互沟通的桥梁。目前，肿瘤分子标志物的研究进展迅速，越来越多的研究成果正在成为肿瘤诊断、治疗、预后及疗效监测的有效工具，是转化医学模式的重要体现。

关键词: 肿瘤, 分子标志物, 转化医学

Abstract:

Recently, the concept of translational medicine has come into being with the fast development of basic medicine such as molecular biology and change of medical mode. The aim of translational medicine is to quickly and effectively translate the basic research achievement of medical biology into theories, technologies, methods and drugs for clinical application, which paves a way from bench to bedside. With the fast research progress of tumor molecular biomarkers, more and more findings have been used for tumor diagnosis, treatment, prognosis and curative effect surveillance, which is an important embodiment of translational medicine.

Key words: tumor, biomarker, translational medicine