上海交通大学学报（医学版）

›› 2012, Vol. 32 ›› Issue (8): 1097-.doi: 10.3969/j.issn.1674-8115.2012.08.029

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Neuregulin1/erbB与神经病理性疼痛

曾路路1,2, 汪 静1,2, 张 昕1, 江 伟2, 杜冬萍1   

  1. 上海交通大学附属第六人民医院 1.疼痛科, 2.麻醉科, 上海 200233
  • 出版日期:2012-08-28 发布日期:2012-08-29
  • 作者简介:曾路路(1986—), 女, 硕士生；电子信箱: zenglu1986@126.com。

Neuregulin1/erbB and neuropathic pain

ZENG Lu-lu1,2, WANG Jing1,2, ZHANG Xin1, JIANG Wei2, DU Dong-ping1   

  1. 1.Pain Management Center, 2.Department of Anesthesiology, the Sixth People´s Hospital, Shanghai Jiaotong University, Shanghai 200233, China
  • Online:2012-08-28 Published:2012-08-29

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摘要：

神经病理性疼痛属于慢性疼痛中的一种，近年来，因其发病机制的复杂性和临床治疗的低治愈率日益受到广大学者的关注。大量研究表明，神经损伤后，大量细胞因子被释放，开启体内多条信号通路，参与疼痛的形成。文章旨在探讨Neuregulin1/erbB信号在神经病理性疼痛中的作用。

关键词: Neuregulin 1, erbB, 神经病理性疼痛

Abstract:

Neuropathic pain is a common chronic pain, and has received more attention recently due to its complicated pathogenesis and ineffective treatment. Many studies have found that a number of cytokines and multiple signaling pathways are involved in the pain procession after never injury. The role of Neuregulin1/erB signaling pathway in neuropathic pain is discussed in this paper.

Key words: Neuregulin 1, erbB, neuropathic pain