›› 2013, Vol. 33 ›› Issue (5): 685-.doi: 10.3969/j.issn.1674-8115.2013.05.036

• 综述 • 上一篇    下一篇


黄宝星, 孙福康   

  1. 上海交通大学 医学院附属瑞金医院泌尿外科, 上海 200025
  • 出版日期:2013-05-28 发布日期:2013-05-28
  • 通讯作者: 孙福康, 电子信箱: sunfukang6@126.com。
  • 作者简介:黄宝星(1988—), 男, 硕士生; 电子信箱: huang_baoxing@126.com。
  • 基金资助:


Research progress of molecular mechanism in primary hyperaldosteronism

HUANG Bao-xing, SUN Fu-kang   

  1. Department of Urology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2013-05-28 Published:2013-05-28
  • Supported by:

    Shanghai Natural Science Foundation,10411960000



关键词: 原发性醛固酮增多症, 离子通道, 信号通路, 基因表达


Primary hyperaldosteronism (PA) is the most common form of endocrine hypertension. With the deepening of studies, the understanding of the pathogenesis of PA has been greatly improved. Elucidating the molecular mechanism of PA has far-reaching significance for a better understanding and therapeutic strategy of PA. In this paper, the abnormalities of ion channel activity, signaling pathways, and gene expression in PA are reviewed, and new ideas are expected to achieve for further research.

Key words: primary hyperaldosteronism, ion channel, signaling pathway, gene expression