目的·采用开源性软件REDCap，以母婴干预预防肥胖队列为示范，阐述基于网络的在线电子数据采集系统构建和数据质控管理。方法·安装REDCap软件，建立母婴干预队列为示范项目。基于研究方案，将队列数据收集的时点和问卷模块列成随访图，设置和创建问卷和电子病历报告表单（electronic case report forms，eCRF），设置数据质量控制程序，设置用户使用权限。结果·在REDCap系统中创建示范项目，建立孕前期、孕期及儿童随访的各期eCRF。经测试后上线，进行数据收集和数据质量控制。设置访问权限实现多中心数据采集。通过质控程序核查和发送数据疑问，进行质控管理。REDCap 数据可导出生成SAS、SPSS、R等多种格式的数据文件供常用统计软件使用。结论·基于REDCap建立的母婴干预队列数据平台和数据管理为项目提供了支撑。该模式可推广运用于其他流行病学人群研究。

Objective · To introduce how to build a data platform of data collection and data management for multi-center birth cohort study by using REDCap. Methods · After the REDCap electronic data capture system was installed and set up, the electronic case report forms (eCRFs) were programmed to collect data in multi-centers. The rules of data quality control were programmed, and different levels of user right for access to data platform were assigned to the data managers and data clerks based on their role in research project. Results · With REDCap system being installed, the example project was created, and a series of eCRFs were established for each stage of preconception, pregnancy and childhood through follow-up. After intensive testing to improve and achieve a stable data platform, standardized trainings were provided to data-related team. The REDCap eCRFs were then put in use online. By assigning different user right of access to data platform, data entry can be from multi- research centers and survey sites. This REDCap data platform supported the cohort project on data collection and data management. Conclusion · The data platform established by using REDCap provides strong support to birth cohorts on data collection and data management. This example project of data platform can be applied to other epidemiological studies.