›› 2012, Vol. 32 ›› Issue (2): 160-.doi: 10.3969/j.issn.1674-8115.2012.02.008

• Original article (Clinical research) • Previous Articles     Next Articles

Prevalence of diabetic macular edema and its related factors

YANG Xiao-lu, ZOU Hai-dong, XU Xun, LIU Kun   

  1. Department of Ophthalmology, the First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China
  • Online:2012-02-28 Published:2012-02-28
  • Supported by:

    National Science and Technology Pillar Program of the “Eleventh Five-Year” Plan, 2007BAI18B07;Key Technological Innovation Project of Sichuan Province, 2010PT004;Shanghai Key Laboratory for Ocular Fundus DiseasesFoundation, 07Z22911


Objective To investigate the prevalence of diabetic macular edema (DME), and analyse its related factors. Methods The clinical data were collected, and related examinations were conducted in 450 patients with diabetes mellitus. The diagnosis of diabetic retinopathy (DR) and DME was made, and the staging of DR and typing of DME were performed. The related factors of DME were analysed, and the relationship between different types of DME and DR stages was explored. Results Among the 450 patients with diabetes mellitus, 168 were diagnosed as DR, and 73 (16.22%) were confirmed as DME. The prevalences of DME in patients with type 1 diabetes mellitus and those with type 2 diabetes mellitus were 8.16% and 17.21% respectively. For patients with no less than 10 years in disease duration, the prevalences of DME were 15.39% and 27.03% respectively in those with type 1 diabetes mellitus and type 2 diabetes mellitus. The prevalences of focal, diffuse, ischemic and proliferative DME in patients with diabetes mellitus were 7.56%, 5.56%, 0.44% and 2.44% respectively. Logistic stepwise regression analysis demonstrated that disease duration of diabetes mellitus and DR staging were independent related factors of prevalence of DME, and DR staging was a common independent related factor of prevalences of different types of DME. Conclusion The prevalence of DME increases with the disease duration of diabetes mellitus and severity of DR, and the severity of DR is related to the prevalences of different types of DME.

Key words: diabetic macular edema, prevalence, related factor