• Review • Previous Articles     Next Articles

Effects and mechanisms of interleukin-6 towards learning and memory

LIANG Shi-qiao1, SU Liang1,2, JIA Yu-ping2, XU Yi-feng1,2   

  1. 1.Department of Psychiatry, Huashan Hospital, Fudan University, Shanghai 200040, China; 2.Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2014-08-28 Published:2014-09-02
  • Supported by:

    Emerging Frontier Technology Joint Research Program of City-Level Hospitals in Shanghai, SHDC12010115


Recent studies show that interleukin-6 (IL-6) influences not only the immune system, but also learning and memory, but the effects and mechanism are still controversial. This paper reviews studies on major signaling pathways and the effects of IL-6 on learning and memory and preliminarily discusses the mechanism and relevant influent factors of IL-6 towards learning and memory.

Key words: interleukin-6, learning, memory, mechanism