›› 2017, Vol. 37 ›› Issue (8): 1156-.doi: 10.3969/j.issn.1674-8115.2017.08.021

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Advances in neuroimaging studies on executive impairment of patients with euthymic bipolar disorder#br#

YANG Tao, ZHAO Guo-qing, FANG Yi-ru, CHEN Jun   

  1. Brain Science and Technology Research Center, Depressive Disorders Program, Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2017-08-28 Published:2017-09-28
  • Supported by:
     National Natural Science Foundation of China, 91232719, 81201056, 81301159; Excellent Young Talents Program of Shanghai Health System, XYQ2011014; Medicine Guidance Project of Shanghai Committee of Science and Technology, 12401906200; National Key Clinical Disciplines at Shanghai Mental Health Center, OMA-MH, 2011-873; Shanghai Clinical Center for Mental Disorders, 2014; The “12th Five-year Plan” of National Key Technologies R&D Program, Ministry of Science and Technology of China, 2012BAI01B04; Excellent Academic Leaders Training Plan of Shanghai Health System, XBR2013087; National High-tech R&D Program of China, “863 Program”, 2015AA020509

Abstract: Bipolar disorder (BD) is a chronic mental illness with high recurrence rate and disability. As one of the core symptoms, cognitive impairment may occurs at every stage of the disease. Evidence from the neuroimaging studies revealed that the abnormal brain volumes, the blood flow and oxygen saturation of key brain areas are related to executive impairment in patients with bipolar disorder. This article reviews current structural and functional neuroimaging studies about the executive impairment of patients with euthymic bipolar disorder and research progresses.

Key words: bipolar disorder, executive impairment, neuroimaging