›› 2017, Vol. 37 ›› Issue (11): 1548-.doi: 10.3969/j.issn.1674-8115.2017.11.017

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Progress of adipocyte plasma membrane associated protein

HUANG Jing-jing, MA Yu-hang, WANG Yu-fan   

  1. Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 201620, China
  • Online:2017-11-28 Published:2018-01-10
  • Supported by:
    National Natural Science Foundation of China, 81600611; Shanghai Pujiang Program, 15PJD032; Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support, 20152231

Abstract:  Adipocyte plasma membrane associated protein (APMAP) is a novel integral membrane protein, widely expressed in many organizations in humans. It promotes the differentiation of preadipocytes to mature adipocytes, so as to maintain normal physiological metabolism function in adipocytes, and plays a major role in adipocytes differentiation. Nowadays, some progress has been made in its role of inflammation and consequently in pathogenesis of gestational diabetes mellitus and other diseases. This paper gives a brief review about the structure and function of APMAP and sums up progress of the current studies.

Key words: adipocyte plasma membrane associated protein, adipocyte differentiation, structure, function

CLC Number: