›› 2009, Vol. 29 ›› Issue (9): 1116-.

• Review • Previous Articles     Next Articles

Effects of chemokines and their receptors in pregnancy immune tolerance

XIAO Shi-jin reviewer, ZHAO Ai-min reviser   

  1. Department of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200001, China
  • Online:2009-09-25 Published:2009-09-29
  • Supported by:

    Shanghai Natural Science Foundation, 072R14072


Pregnancy immune tolerance is a special type of peripheral immunological tolerance formed by maternal immune system during pregnancy, which urges maternal immune system not to reject fetus as half-allogeneic graft. Chemokines and their receptors play important roles in induced immune tolerance as participating in activation and migration of immunocytes. This article reviews the effects of chemokines and their receptors in pregnancy immune tolerance.

Key words: pregnancy, immune tolerance, chemokine, chemokine receptor

CLC Number: