Abstract:

Objective To investigate the clinical characteristics and prognosis of small cell carcinoma of sophagus. Methods Fifteen patients with small cell carcinoma of esophagus diagnosed by X-ray, chest CT and esophagoscopy and confirmed by pathology were selected, and the clinical characteristics and prognosis were analysed. Results The median survival time of these 15 patients was 8.82 months, and the survival time ranged from 29 d to 26 months. The 6-month survival rate was 53%, 1-year survival rate was 20%, 2-year survival rate was 7% and 3-year survival rate was 0. The median survival time of patients with single operation, single chemotherapy and comprehensive treatment was 8 months, 4.1 months and 11.83 months, respectively. Conclusion The optimal therapy for small cell carcinoma of esophagus remains undetermined. Comprehensive treatment with chemotherapy and radiotherapy may yield longer survival time than single treatment.

Key words: small cell carcinoma of esophagus, therapy, prognosis