JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2020, Vol. 40 ›› Issue (7): 943-949.doi: 10.3969/j.issn.1674-8115.2020.07.013

• Original article (Clinical research) • Previous Articles     Next Articles

Prevalence of chronic periodontitis in peritoneal dialysis patients and its correlation with dialysis adequacy

DENG Hai1, TONG Yan1, Kristine SUN2, XIA Xin-yi2, LI Pu1, ZHANG Chun-li1, HU Chun1, SONG Zhong-chen2, LIU Ying-li1   

  1. 1. Department of Nephrology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China; 2. Department of Periodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai 200011, China
  • Online:2020-07-28 Published:2020-09-23
  • Supported by:
    Clinical Research Program of Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine (jylj2018011).

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Abstract: Objective · To analyze the prevalence of chronic periodontitis (CP) in the peritoneal dialysis patients based on a single-center population, and explore the correlation between the severity of CP and the adequacy of peritoneal dialysis. Methods · A total of 57 patients undergoing peritoneal dialysis in the Department of Nephrology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from December 2018 to December 2019 were included in the study. Baseline data, indicators of dialysis adequacy, including Kt/V, creatinine clearance rate, etc., and other related biochemical indicators were collected, and at the same time the CP-related indicators including clinical attachment loss, gingival index and probing depth were collected. The indicators of dialysis adequacy or their control rates of the patients with different severity of CP were compared. Pearson correlation analysis and linear regression analysis were used to explore the correlation between CP-related indexes and the indicators of dialysis adequacy. Results · All the patients undergoing peritoneal dialysis included in this study have moderate to severe CP. The prevalence of moderate CP was 24.6%, and the prevalence of severe CP was 75.4%. The proportion of moderate to severe anemia in the severe CP group was higher than that in the moderate CP group (28.0% vs 14.3%), but the difference was not statistically significant (P>0.05). Between the moderate and severe CP group, there was no statistical difference in the indicators of dialysis adequacy and their control rates (P>0.05). And there was no correlation between CP-related indexes and the indicators of dialysis adequacy as well (P>0.05). Conclusion · The prevalence of moderate to severe CP is very high in the peritoneal dialysis patients, in whom those with severe CP may have a tendency to develop moderate to severe anemia. There is no correlation between the severity of CP and dialysis adequacy.

Key words: peritoneal dialysis, chronic periodontitis (CP), dialysis adequacy, anemia

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