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Long-term effects of gestational diabetes mellitus on mothers and offspring and strategies of postpartum follow up

HUANG Ying, ZHAO Li, FANG Fang, ZHEN Qin, YAN Shuai, WANG Yu-fan   

  1. Department of Endocrinology and Metabolism, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai 200080, China
  • Online:2016-09-28 Published:2016-10-31
  • Supported by:

    National Natural Science Foundation of China, 81300637; Shangai Pujiang Talent Program,15PJD032;Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support,20152231


Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance that is first identified during pregnancy, excluding diabetic patients diagnosed before pregnancy. GDM not only can cause adverse events in mother and infant during pregnancy, but also has long-term effects after pregnancy. GDM can increase the prevalence of type 2 diabetes, cardiovascular disease, metabolic syndrome, and depression in mothers and elevates risks of abnormal glucose metabolism, hypertension, and obesity in offspring. Effective postpartum follow up and intervention can reduce those risks. This article reviews long term effects of GDM on mothers and offspring and strategies and methods of postpartum follow up.

Key words: gestational diabetes, long-term outcomes, postpartum management