Abstract: Objective · To investigate the value of percutaneous oxygen saturation measurement combined with echocardiography remote consultation in the screening and referral of neonatal critical congenital heart disease (CCHD) in remote areas. Methods · The live newborns who were born between 2014 and 2016 in Chongming District of Shanghai were taken as the objects of study, the percutaneous oxygen saturation was measured at 24-48 h after birth. The data were classified according to congenital heart disease segmental diagnosis standard in the mean time, and the echocardiography was preliminary diagnosed after the remote consultation through WeChat platform. Results · A total of 4 450 live newborns were screened, 11 cases were positive, 6 cases were preliminary diagnosed as CCHDthe echocardiography remote consultation, and 1 case of negative screening was later diagnosed as pulmonary atresia with ventricular septal defectechocardiography. The sensitivity of percutaneous oxygen saturation screening for CCHD was 85.71%, the specificity was 99.89%, the false positive rate was 0.11%, the false negative rate was 14.29%, and the area under the ROC curve was 0.928. Conclusion · CCHD can be screened out effectivelypercutaneous oxygen saturation combined with the WeChat platform, and it can be preliminary diagnosedthe echocardiography remote consultation, which can provide timely referral and avoid unnecessary referral. This screening model is simple and practical. It has practical value in remote areasare lack of professional medical technicians for the diagnosis and treatment of congenital heart disease.

Key words: congenital heart disease, oxygen saturation, screening, echocardiography, remote consultation