›› 2019, Vol. 39 ›› Issue (9): 1089-.doi: 10.3969/j.issn.1674-8115.2019.09.024

• Review • Previous Articles     Next Articles

Progress of transcranial direct current stimulation for treatment of obsessive-compulsive disorder

CHENG Jia-yue, WANG Zhen   

  1. Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2019-09-28 Published:2019-11-02
  • Supported by:
    National Natural Science Foundation of China, 81671340; Municipal Human Resources Development Program for Outstanding Leaders in Medical Disciplines in Shanghai, 2017BR058; Shanghai Municipal Education Commission— Gaofeng Clinical Medicine Support, 20161321)。

Abstract: Obsessive-compulsive disorder is a disabling disease with symptoms of repeated and persistent unwanted intrusive thoughts and compulsive behaviors. The current first-line treatment methods mainly include psychopharmacology, psychotherapy, and the combination of both, but nearly 40% patients still show no response to conventional treatment. Among the recently developed treatments, non-invasive brain stimulation techniques, such as transcranial direct current stimulation (tDCS), are expected to alleviate the symptoms of various psychiatric disorders and improve cognitive function. tDCS has been applied to the treatment of depression, schizophrenia, generalized anxiety disorder and other mental diseases, and has achieved definite clinical effect. However, there are few studies about tDCS applying to the obsessive-compulsive disorder, especially in the number of randomized controlled trials. Most of the studies are open trials and case reports, and the results are inconsistent.reviewing the effect of tDCS in treating obsessive-compulsive disorder patients in existing reports, the possibility of applying tDCS widely to treating obsessive-compulsive disorder in the future is analyzed.

Key words: obsessive-compulsive disorder, transcranial direct current stimulation, non-invasive brain stimulation techniques, neuromodulation

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