Abstract: At present, a large number of studies have proved the important role of the nerve-gut-brain axis in mental disorders, and focused on the correlation between gut microbiota and mental disorders and the potential regulating mechanisms. This paper summarizes the current research status of gut microflora in several mental disorders, such as depression, anxiety and substance disorders, into provide more clinical evidence for gut microflora as a new target for treatment.

Key words: gut microbiota, nerve-gut-brain axis, depression, anxiety, substance disorders