Biological and angiogenic effects of enamel matrix derivative on periodontal regeneration-related cells

doi:10.3969/j.issn.1674-8115.2021.08.017

Abstract

Abstract:

Enamel matrix protein has been proved to promote periodontal regeneration, and later developed into enamel matrix derivative (EMD). At present, EMD has been used in clinic for more than 20 years, and a number of clinical studies have shown that it also has a prominent role in periodontal regeneration. Angiogenesis also plays an essential role in tissue regeneration. This process allows the transportation of numerous cytokines to tissue defect areas via newly formed blood vessel, which can then stimulate periodontal regeneration. Several researches have indicated that EMD can stimulate angiogenesis. In this paper, the effects of EMD on periodontal regeneration-related cells and angiogenesis are reviewed.

Key words: enamel matrix derivative (EMD), angiogenesis, vascular endothelial cell, periodontal regeneration

CLC Number:

R781.4⁺2

Chi-hsiang CHUANG, Jia-chen DONG, Rong SHU. Biological and angiogenic effects of enamel matrix derivative on periodontal regeneration-related cells[J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(8): 1099-1102.

TrendMD

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