Journal of Shanghai Jiao Tong University (Medical Science) ›› 2023, Vol. 43 ›› Issue (5): 560-570.doi: 10.3969/j.issn.1674-8115.2023.05.006
• Basic research • Previous Articles
LI Qinglin1(), WANG Wenbo2(), LIU Wei2()
Received:
2023-01-03
Accepted:
2023-04-28
Online:
2023-05-28
Published:
2023-07-11
Contact:
WANG Wenbo,LIU Wei
E-mail:qinglinli346@163.com;wangwenbo0903@126.com;liuwei_md@126.com
Supported by:
CLC Number:
LI Qinglin, WANG Wenbo, LIU Wei. Bioinformatics analysis of pathological mechanism of degenerated tendon via stress deprivation[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2023, 43(5): 560-570.
Add to citation manager EndNote|Ris|BibTeX
URL: https://xuebao.shsmu.edu.cn/EN/10.3969/j.issn.1674-8115.2023.05.006
1 | WANG J H. Mechanobiology of tendon[J]. J Biomech, 2006, 39(9): 1563-1582. |
2 | HEO S J, SZCZESNY S E, KIM D H, et al. Expansion of mesenchymal stem cells on electrospun scaffolds maintains stemness, mechano-responsivity, and differentiation potential[J]. J Orthop Res, 2018, 36(2): 808-815. |
3 | FRIZZIERO A, FINI M, SALAMANNA F, et al. Effect of training and sudden detraining on the patellar tendon and its enthesis in rats[J]. BMC Musculoskelet Disord, 2011, 12: 20. |
4 | WUNDERLI S L, BLACHE U, BERETTA PICCOLI A, et al. Tendon response to matrix unloading is determined by the patho-physiological niche[J]. Matrix Biol, 2020, 89: 11-26. |
5 | CHEN Z, ZHOU B, WANG X, et al. Synergistic effects of mechanical stimulation and crimped topography to stimulate natural collagen development for tendon engineering[J]. Acta Biomater, 2022, 145: 297-315. |
6 | SMYTH L M, TAMURA K, OLIVEIRA M, et al. Capivasertib, an AKT kinase inhibitor, as mnotherapy or in combination with fulvestrant in patients with AKT1 E17K-mutant, ER-positive metastatic breast cancer[J]. Clin Cancer Res, 2020, 26(15): 3947-3957. |
7 | FUJIMOTO Y, MORITA T Y, OHASHI A, et al. Combination treatment with a PI3K/Akt/mTOR pathway inhibitor overcomes resistance to anti-HER2 therapy in PIK3CA-mutant HER2-positive breast cancer cells[J]. Sci Rep, 2020, 10(1): 21762. |
8 | CHEN J, ZHANG X, LIU X, et al. Ginsenoside Rg1 promotes cerebral angiogenesis via the PI3K/Akt/mTOR signaling pathway in ischemic mice[J]. Eur J Pharmacol, 2019, 856: 172418. |
9 | EL HIANI Y, EGOM E E, DONG X P. mTOR signalling: jack-of-all-trades[J]. Biochem Cell Biol, 2019, 97(1): 58-67. |
10 | CONG X X, RAO X S, LIN J X, et al. Activation of AKT-mTOR signaling directs tenogenesis of mesenchymal stem cells[J]. Stem Cells, 2018, 36(4): 527-539. |
11 | LIM J, MUNIVEZ E, JIANG M M, et al. mTORC1 signaling is a critical regulator of postnatal tendon development[J]. Sci Rep, 2017, 7(1): 17175. |
12 | ZASECK L W, MILLER R A, BROOKS S V. Rapamycin attenuates age-associated changes in tibialis anterior tendon viscoelastic properties[J]. J Gerontol A Biol Sci Med Sci, 2016, 71(7): 858-865. |
13 | TUMMINIA S J, MITTON K P, ARORA J, et al. Mechanical stretch alters the actin cytoskeletal network and signal transduction in human trabecular meshwork cells[J]. Invest Ophthalmol Vis Sci, 1998, 39(8): 1361-1371. |
14 | SARASA-RENEDO A, TUNÇ-CIVELEK V, CHIQUET M. Role of RhoA/ROCK-dependent actin contractility in the induction of tenascin-C by cyclic tensile strain[J]. Exp Cell Res, 2006, 312(8): 1361-1370. |
15 | RIDLEY A J, HALL A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors[J]. Cell, 1992, 70(3): 389-399. |
16 | TERAMURA T, TAKEHARA T, ONODERA Y, et al. Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells[J]. Biochem Biophys Res Commun, 2012, 417(2): 836-841. |
17 | CHEN J C, JACOBS C R. Mechanically induced osteogenic lineage commitment of stem cells[J]. Stem Cell Res Ther, 2013, 4(5): 107. |
18 | MATSSON H, EASON J, BOOKWALTER C S, et al. Alpha-cardiac actin mutations produce atrial septal defects[J]. Hum Mol Genet, 2008, 17(2): 256-265. |
19 | TSAO J, VERNET D A, GELFAND R, et al. Myostatin genetic inactivation inhibits myogenesis by muscle-derived stem cells in vitro but not when implanted in the mdx mouse muscle[J]. Stem Cell Res Ther, 2013, 4(1): 4. |
20 | LI A, SU X, TIAN Y, et al. Effect of actin alpha cardiac muscle 1 on the proliferation and differentiation of bovine myoblasts and preadipocytes[J]. Animals (Basel), 2021, 11(12): 3468. |
21 | FERRARA N, ADAMIS A P. Ten years of anti-vascular endothelial growth factor therapy[J]. Nat Rev Drug Discov, 2016, 15(6): 385-403. |
22 | CARMELIET P. Angiogenesis in health and disease[J]. Nat Med, 2003, 9(6): 653-660. |
23 | PUFE T, PETERSEN W J, MENTLEIN R, et al. The role of vasculature and angiogenesis for the pathogenesis of degenerative tendons disease[J]. Scand J Med Sci Sports, 2005, 15(4): 211-222. |
24 | TEMPFER H, SPITZER G, LEHNER C, et al. VEGF-D-mediated signaling in tendon cells is involved in degenerative processes[J]. FASEB J, 2022, 36(2): e22126. |
25 | PERRY S M, MCILHENNY S E, HOFFMAN M C, et al. Inflammatory and angiogenic mRNA levels are altered in a supraspinatus tendon overuse animal model[J]. J Shoulder Elbow Surg, 2005, 14(1 suppl s): 79S-83S. |
26 | PETERSEN W, VAROGA D, ZANTOP T, et al. Cyclic strain influences the expression of the vascular endothelial growth factor (VEGF) and the hypoxia inducible factor 1 alpha (HIF-1alpha) in tendon fibroblasts[J]. J Orthop Res, 2004, 22(4): 847-853. |
27 | PETERSEN W, PUFE T, UNTERHAUSER F, et al. The splice variants 120 and 164 of the angiogenic peptide vascular endothelial cell growth factor (VEGF) are expressed during Achilles tendon healing[J]. Arch Orthop Trauma Surg, 2003, 123(9): 475-480. |
28 | SANDRI M. New findings of lysosomal proteolysis in skeletal muscle[J]. Curr Opin Clin Nutr Metab Care, 2011, 14(3): 223-229. |
29 | HU J, DING X, TIAN S, et al. TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7[J]. Cell Death Dis, 2021, 12(4): 391. |
30 | XU K, LIN C, MA D, et al. Spironolactone ameliorates senescence and calcification by modulating autophagy in rat tendon-derived stem cells via the NF-κB/MAPK pathway[J]. Oxid Med Cell Longev, 2021, 2021: 5519587. |
31 | WANG H, GAO N, LI Z, et al. Autophagy alleviates melamine-induced cell death in PC12 cells via decreasing ROS level[J]. Mol Neurobiol, 2016, 53(3): 1718-1729. |
32 | PAN H, CAI N, LI M, et al. Autophagic control of cell ‘stemness’[J]. EMBO Mol Med, 2013, 5(3): 327-331. |
33 | VESSONI A T, MUOTRI A R, OKAMOTO O K. Autophagy in stem cell maintenance and differentiation[J]. Stem Cells Dev, 2012, 21(4): 513-520. |
34 | MARIÑO G, NISO-SANTANO M, BAEHRECKE E H, et al. Self-consumption: the interplay of autophagy and apoptosis[J]. Nat Rev Mol Cell Biol, 2014, 15(2): 81-94. |
35 | RYTER S W, MIZUMURA K, CHOI A M. The impact of autophagy on cell death modalities[J]. Int J Cell Biol, 2014, 2014: 502676. |
36 | WU B, CHEN J, DELA ROSA T, et al. Cellular response and extracellular matrix breakdown in rotator cuff tendon rupture[J]. Arch Orthop Trauma Surg, 2011, 131(3): 405-411. |
37 | ARBI S, EKSTEEN E C, OBERHOLZER H M, et al. Premature collagen fibril formation, fibroblast-mast cell interactions and mast cell-mediated phagocytosis of collagen in keloids[J]. Ultrastruct Pathol, 2015, 39(2): 95-103. |
[1] | XIE Xiaolei, JIANG Peixin, ZHANG Jinghong, MO Junjian, WU Kefan, ZENG Kangyi. A review of RIZ1 regulation of the signal pathways in obesity and tumors [J]. Journal of Shanghai Jiao Tong University (Medical Science), 2023, 43(1): 114-119. |
[2] | HAN Xiaxia, JIANG Yang, GU Shuangshuang, DAI Dai, SHEN Nan. Transcriptomic analysis of metabolic characteristics of the immune cells in systemic lupus erythematosus patients [J]. Journal of Shanghai Jiao Tong University (Medical Science), 2022, 42(9): 1197-1207. |
[3] | JIN Bu, YUAN Ying, CHEN Wanyu, XU Hudong, HUANG Xiaolei, HE Jialu, YU Hong. Involvement of miRNA target genes in esophageal squamous cell carcinoma through ubiquitination based on GEO database [J]. Journal of Shanghai Jiao Tong University (Medical Science), 2022, 42(4): 464-471. |
[4] | GONG Qiyu, CHEN Lei. Role of circulating and infiltrating B cells in immune microenvironment of colorectal cancer by multi-omics data profiling [J]. Journal of Shanghai Jiao Tong University (Medical Science), 2022, 42(4): 472-481. |
[5] | XU Jingxuan, DU Shaoqian, CAO Yuan, WANG Hongxia, HUANG Weiyi. MMP14 expression in pancreatic cancer and its correlation with characteristics of tumor immune microenvironment [J]. Journal of Shanghai Jiao Tong University (Medical Science), 2022, 42(3): 312-322. |
[6] | Jianru WANG, Guangcao PENG, Mingjun ZHU. Screening potential hub genes associated with myocardial ischemia-reperfusion injury in mice based on GEO database and bioinformatics analysis [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2022, 42(1): 51-62. |
[7] | Ying XU, Yi-min CHU, Da-ming YANG, Ji LI, Hai-qin ZHANG, Hai-xia PENG. Construction of a metastasis prediction model of microsatellite instability-high colorectal cancer based on differentially expressed gene assembly [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(9): 1197-1206. |
[8] | Bei-bei XUAN, Sai-nan GONG, Jia-li LIU, Quan QUAN, Yu MENG, Xiao-ling MU. Expression and clinical significance of DNA polymerase θ in endometrial cancer [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(9): 1207-1214. |
[9] | Yin LIU, Tao YANG, Yu-sai XIE, Yu-zhu WANG. Screening of key genes and pathways involved in lupus nephritis based on GEO database [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(6): 749-755. |
[10] | Lu-di YANG, Gao-ming WANG, Ren-hao HU, Xiao-hua JIANG, Ran CUI. Identification of core genes in pancreatic cancer progression by bioinformatics analysis [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(5): 571-578. |
[11] | Qi-sheng GU, Mi-li ZHANG, Can CAO, Ji-kun LI. Association of alternative splicing and tumor immune in gastric cancer based on TCGA data set [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(4): 448-458. |
[12] | Ren-yan WU, Xiao-lin GUO, Deng-li HONG, Lei CHEN. Identification of potential therapeutic target genes in pediatric acute leukemia of ambiguous lineage based on bioinformatics analysis [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(3): 320-327. |
[13] | Yan-ru MA, Lin-hua JI, Tian-ying TONG, Yu-qing YAN, Chao-qin SHEN, Xin-yu ZHANG, Ying-ying CAO, Jie HONG, Hao-yan CHEN. Establishment and validation of prognostic prediction model of colorectal cancer based on single-cell RNA sequencing [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(2): 159-165. |
[14] | Yuan-xin HUANG, Dong-mei LAI. Application of proteomics to the study of gynecological diseases [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(2): 233-240. |
[15] | Zhuo-yi YANG, Hui CHEN, Si-yi BAI, Pameila PERHATI, Jing-li HOU, Yun-sheng YUAN. Phosphoproteomic analysis of concanavalin A-induced hepatocytes injury [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(1): 1-7. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||