›› 2010, Vol. 30 ›› Issue (6): 639-.

• Monographic report (Depressive disorder) • Previous Articles     Next Articles

Efficacy of integrated-model management on chronic depression

WANG Zuo-wei1,2, FANG Fang2, LU Zhi-ping2, WANG Ping2, CHEN Yin-di2, ZHANG Shao-ping2, FANG Yi-ru1   

  1. 1.Division of Mood Disorder, Shanghai Mental Health Center, School of Medicine, Shanghai Jiaotong University, Shanghai 200030, China；2.Hongkou District Mental Health Center of Shanghai, Shanghai 200083, China
  • Online:2010-06-25 Published:2010-06-28
  • Supported by:

    High-Tech R&D Program of China, 2006AA02Z430；Shanghai Outstanding Youth Training Program, 08GWQ030；Shanghai Municipal Health Bureau Foundation, 2008Y056；Foundation from Hongkou District, Shanghai, 0801-03

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Abstract:

Objective To evaluate the short-term efficacy of integrated-model management on chronic depression. Methods Outpatients with depression and Hamilton Rating Scale for Depression-17 (HAMD-17)≥3 and without acute episode openly entered management group (n=30) and control group (n=30). Patients in management group received regular clinical care, group therapy intervention, self-help group and self-management, while those in control group only received regular clinical care. The primary outcomes was changes of HAMD-17 scores from baseline to endpoint (the end of the sixth month), and the secondary outcomes included remission rate, recurrence rate and changes of Social Disability Screening Schedule (SDSS) scores from baseline to endpoint. Results Analysis of covariance (ANCOVA) revealed that there were significant differences in the changes of HAMD-17 scores and SDSS scores from baseline to endpoint between management group and control group (F=46.80, P=0.00; F=49.29, P=0.00). However, Fisher's exact test indicated that there was no significant difference in the rates of remission and recurrence between management group and control group (P>0.05). Conclusion The integrated-model management may significantly relieve residual symptoms and improve social function of patients with chronic depression.

Key words: depression, residual symptom, remission, self-management, integrated model