›› 2011, Vol. 31 ›› Issue (5): 672-.doi: 10.3969/j.issn.1674-8115.2011.05.031

• Review • Previous Articles     Next Articles

Research progress of susceptible genes and genetic epidemiology of prostate cancer

WU Qi-jun1, XU Jian-feng2, SHI Rong1   

  1. 1.School of Public Health, Shanghai Jiaotong University, Shanghai 200025, China; 2.Fudan-VARI Genetic Epidemiology Research Centre, Fudan University, Shanghai 200433, China
  • Online:2011-05-28 Published:2011-05-27


Many genetic researches have suggested that genetic factor plays an important role in the development of prostate cancer. Meanwhile, some case-control studies and population-based cohort studies have also revealed the complex genetic epidemiology characters of prostate cancer. This paper not only analyses the relationship between epidemic exposure factors, susceptible genes and prostate cancer, but also points out the present status of genetic epidemiology of prostate cancer and the prospects of research in this aspect.

Key words: prostate cancer, susceptible gene, genome-wide association study, single nucleotide polymorphisms, genetic epidemiology