›› 2011, Vol. 31 ›› Issue (5): 676-.doi: 10.3969/j.issn.1674-8115.2011.05.032

• Review • Previous Articles     Next Articles

Pathogenesis of complications of pre-eclampsia and eclampsia

LE Yi-ping, LIN Jian-hua   

  1. Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
  • Online:2011-05-28 Published:2011-05-27

Abstract:

Pre-eclampsia is a disorder that is unique to pregnancy, with gestational hypertension and proteinuria as main clinical manifestations. Without proper management, pre-eclampsia may develop to eclampsia and cause a series of complications involving cardiovascular, renal, neurologic, hematologic and gastrointestinal systems, which may threaten lives of mothers and infants. The pathogenesis of pre-eclampsia is still unclear, and reduced placental perfusion is considered to be the pathological mechanism, which may result in endothelial cell injury and further aggravate dysfunction of maternal systems. This paper reviews the pathogenesis, incidence and research progress of complications of pre-eclampsia and eclampsia.

Key words: pre-eclampsia, eclampsia, complication