›› 2011, Vol. 31 ›› Issue (6): 858-.doi: 10.3969/j.issn.1674-8115.2011.06.040

• Review • Previous Articles     Next Articles

Research progress of single nucleotide polymorphisms of cytochrome P450 4F2

LI Jie-hui, XU Jian-jun   

  1. The Second Affiliated Hospital to Nanchang University, Nanchang 330006, China
  • Online:2011-06-28 Published:2011-06-27


Cytochrome P450 (CYP) 4F2, a member of the CYP4F enzyme subfamily, takes part in a series of biochemical reaction in vivo. Recent researches have revealed the new mechanism the enzyme plays in the cardiovascular and hematological fields, such as essential hypertension, myocardial infarction, stroke and metabolism of arachidonic acid and warfarin.

Key words: cytochrome P450, single nucleotide polymorphisms, pathophysiology