Abstract:

Objective To investigate the effects of ovarian poor response on incidences of hypertensive disorders complicating pregnancy after in vitro fertilization-embryo transfer (IVF-ET). Methods Patients (≤35 years old）with successful delivery after IVF-ET were divided into ovarian poor response group (number of retrieved oocytes≤4, n=92) and ovarian normal response group (number of retrieved oocytes 8-12, n=92). Patients in two groups were matched for age, type of infertility, daily dose of recombinant follicle-stimulating hormone, singleton or twin pregnancy and therapeutic regimen (in vitro fertilization/intracytoplasmic sperm injection), and the incidences of hypertensive disorders complicating pregnancy and preeclampsia were compared between two groups. Results There was no significant difference in the incidences of hypertensive disorders complicating pregnancy and preeclampsia between ovarian poor response group and ovarian normal response group (P>0.05). There was also no significant difference in the birth weight of neonates, duration of pregnancy, rates of viginal delivery and rates of live birth between two groups (P>0.05). Conclusion Ovarian poor response may have no significant effect on incidences of hypertensive disorders complicating pregnancy after IVF-ET.

Key words: in vitro fertilization-embryo transfer, ovarian poor response, hypertensive disorders complicating pregnancy, preeclampsia