›› 2012, Vol. 32 ›› Issue (7): 952-.doi: 10.3969/j.issn.1674-8115.2012.07.028

• 综述 • 上一篇    下一篇


毛亚静, 杨祖菁   

  1. 上海交通大学 医学院附属新华医院妇产科, 上海 200092
  • 出版日期:2012-07-28 发布日期:2012-08-17
  • 通讯作者: 杨祖菁, 电子信箱: yzujing@sohu.com。
  • 作者简介:毛亚静(1987—), 女, 硕士生;电子信箱: huangdumaomao@sina.com。

Research progress of pathogenesis of microparticles in preeclampsia

MAO Ya-jing, YANG Zu-jing   

  1. Department of Obstetrics and Gynecology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
  • Online:2012-07-28 Published:2012-08-17



关键词: 微粒, 子前期, 妊娠, 发病机制


Preeclampsia (PE) is a pregnancy-specific multi-system dysfunction disease, which is one of the main causes of maternal and infant mortality. The pathogenesis of PE is not clear, inflammation, coagulation function changes, platelet activation and endothelial damage may have significant impact on the pathological process of PE, and studies have confirmed that microparticles (MP) play an important role in the above process. The research progress of generation and characteristics of MP, the changes of contents of MP in systemic circulation during pregnancy, and the pathogenesis of MP in PE is reviewed, and the prospect of MP in the diagnosis and treatment of PE is explored in this paper.

Key words: microparticles, preeclampsia, pregnancy, pathogenesis