上海交通大学学报(医学版)

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Slitrk家族在精神疾病中作用的研究现状

王 媛1,肖泽萍2   

  1. 上海交通大学医学院 1.附属精神卫生中心, 2.精神卫生学系, 上海 200030
  • 出版日期:2014-09-28 发布日期:2014-09-26
  • 通讯作者: 肖泽萍, 电子信箱: xiaozeping@gmail.com。
  • 作者简介:王 媛(1983—), 女, 博士生; 电子信箱: wangyuan129@163.com。
  • 基金资助:

    国家自然科学基金(81171280,81301153);国家临床重点专科-上海市精神卫生中心基金(2011-873);上海市精神卫生中心重点特色专科基金(2013-YJTSZK-02)

Research status of Slitrk family for mental disorders

WANG Yuan1, XIAO Ze-ping2   

  1. 1.Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China; 2.Department of Psychiatry, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2014-09-28 Published:2014-09-26
  • Supported by:

    National Natural Science Foundation of China,81171280,81301153;National Key Clinical Disciplines at Shanghai Mental Health Center, 2011-873;The Key Characteristic Specialist Department of Shanghai Mental Health Center, 2013-YJTSZK-02

摘要:

精神疾病的病因学研究一直是精神医学领域研究的重点和热点,但多数精神疾病的病因及发病机制目前仍未能完全阐明,遗传学是研究最为关注的领域之一。近年来,Slitrk家族在精神疾病发病机制中的作用逐渐受到研究者的重视。该文就Slitrk家族在精神疾病中作用的研究现状作一综述。

关键词: 精神疾病, Tourette综合征, 强迫症, 拔毛癖, 精神分裂症, Slitrk

Abstract:

Studies of mental disorders always emphasize the etiology. Currently the etiology and pathogenesis of most mental disorders are still not well clarified. The genetics is one of fields that attract most attention. In recent years, researchers gradually focus on the effects of Slitrk family on the pathogenesis of mental disorders. This paper reviews studies on the Slitrk family for mental disorders.

Key words: mental disorders, Tourette's syndrome, obsessive-compulsive disorder, trichotillomania, schizophrenia, Slitrk