上海交通大学学报（医学版）

›› 2010, Vol. 30 ›› Issue (10): 1281-.doi: 10.3969/j.issn.1674-8115.2010.10.023

• 综述 • 上一篇    下一篇

难治性抑郁症患者工作记忆及功能性神经影像研究进展

陈 俊, 综述；方贻儒, 审校   

  1. 上海交通大学 医学院附属精神卫生中心心境障碍科, 上海 200030
  • 出版日期:2010-10-25 发布日期:2010-10-27
  • 作者简介:陈 俊（1977—）, 男, 主治医师, 博士, 讲师；电子信箱: doctorcj2010@gmail.com。
  • 基金资助:

    “十五”国家科技攻关计划(2004BA720A21-02)；国家高技术研究发展计划（“863”计划）(2006AA02Z430)；上海市“登山行动计划”(064119533)；上海交通大学医学院自然科学基金(09XJ21024)

Progress of the research of working memory and functional neuroimaging in patients with treatment resistant depression

CHEN Jun, reviewer；FANG Yi-ru, reviser   

  1. Division of Mood Disorder, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, China
  • Online:2010-10-25 Published:2010-10-27
  • Supported by:

    the “10th Five-year Plan” of the Key Technology Research and Development Program Foundation of China, 2004BA720A21-02；National High Technology Research and Development Program of China, 2006AA02Z430；the “Climbing Mountain Action Plan” Program of Shanghai, China, 064119533；Natural Science Foundation of Shanghai Jiaotong University School of Medicine, 09XJ21024

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摘要：

难治性抑郁症患者的工作记忆及功能性神经影像学的研究有助于揭示难治性抑郁症患者认知功能损害的特征，有助于临床医师重视难治性抑郁症患者的认知功能损害及其治疗，最终提高患者的生活质量，减轻患者家庭及社会疾病负担。文章对难治性抑郁症患者工作记忆及其功能性神经影像研究进展作一综述。

关键词: 难治性抑郁症, 认知功能, 工作记忆, 神经影像学

Abstract:

Studies on working memory and functional neuro-imaging of treatment resistant depression (TRD) patients may take greatly benefits for us to reveal the characteristics of cognitive impairments and for clinicians to pay more attention to cognitive impairments and treatment of patients with TRD, which finally improve the quality of life and decrease family and social disease burden. The working memory and functional neuroimaging of TRD patients are reviewed in this paper.

Key words: treatment resistant depression, cognitive function, working memory, neuroimaging