上海交通大学学报（医学版）

上海交通大学学报（医学版）

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儿童难治性支原体肺炎诊治进展

梅玉霞1,2，丁立人2，庄 承2，陈若华1   

  1. 1.第二军医大学附属长海医院儿科， 上海 200433； 2.上海市第七人民医院儿科， 上海 200137
  • 出版日期:2015-02-28 发布日期:2015-02-27
  • 作者简介:梅玉霞（1975—），女，硕士生; 电子信箱: 502648466@qq.com。

Progresses of diagnosis and treatment of children with refractory mycoplasma pneumoniae

MEI Yu-xia1,2, DING Li-ren2, ZHUANG Cheng2, CHEN Ruo-hua1   

  1. 1.Department of Pediatrics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China; 2.Department of Pediatrics, Shanghai Seventh People's Hospital, Shanghai 200137, China
  • Online:2015-02-28 Published:2015-02-27

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摘要：

肺炎支原体（MP）是引起儿童呼吸道感染的常见病原菌。MP感染通常是一个自限性、良性过程，大多经大环内酯类治疗有效。但近年来发现，部分患儿虽经正规大环内酯类抗生素治疗1周或1周以上，其临床症状和影像学表现仍无明显改善，病情加重或迁延不愈，甚至出现一些严重的后遗症，导致难治性支原体肺炎（RMPP）的发生。RMPP病例呈逐年增多趋势，在早期诊断和治疗上存在很多困难。该文就RMPP诊断和治疗进展作一综述。

关键词: 肺炎支原体, 难治性, 肺炎, 儿童, 感染

Abstract:

Mycoplasma pneumoniae (MP) is a common pathogen that can cause communityacquired pneumonia of children. The infection of MP is usually a benign and self-limited process and can be effectively treated with macrolides. But in recent years, it was discovered that clinical symptoms and imaging findings of some cases did not improve after being regularly treated with macrolide antibiotics for more than 1 week. Their conditions were worse or protracted. Even some serious sequelae developed and resulted in refractory mycoplcasma pneumoniae pneumonia (RMPP). Cases of RMPP increase year by year and there are many difficulties for early diagnosis and treatment. This paper reviews progresses of the diagnosis and treatment of RMPP.

Key words: mycoplasma pneumoniae, refractory, pneumonia, children, infection