上海交通大学学报（医学版）

上海交通大学学报（医学版）

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磁共振技术研究小脑在强迫症发病中作用的研究进展

许婷婷，王振   

  1. 上海交通大学 医学院附属精神卫生中心，上海 200030
  • 出版日期:2017-05-28 发布日期:2017-05-31
  • 作者简介:许婷婷（1993—），女，硕士生；电子信箱：suetina_hsu@foxmail.com。
  • 基金资助:

    国家自然科学基金（81671340）；上海交通大学“医工交叉研究基金”（YG2013MS65）

Research progress of magnetic resonance technology in investigating the role of cerebellar in the pathophysiology of obsessive-compulsive disorder

XU Ting-ting, WANG Zhen   

  1. Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2017-05-28 Published:2017-05-31
  • Supported by:

    National Natural Science Foundation of China, 81671340; Biomedical Engineering Cross Research Foundation of Shanghai Jiao Tong University, YG2013MS65

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摘要：

强迫症是一种慢性致残性的精神障碍，核心表现为强迫观念和强迫行为，病因及发病机制目前尚未完全明确。近年来磁共振技术因其无辐射、非侵入性等优点已被广泛用于精神疾病的研究。一些磁共振研究结果发现强迫症患者存在小脑结构及功能的改变，且这些改变与强迫症的发生存在一定的联系。该文对磁共振技术探索小脑在强迫症发病中所起作用的研究进展进行综述。

关键词: 强迫症, 小脑, 磁共振, 弥散张量成像

Abstract:

Obsessive-compulsive disorder (OCD) is a chronic disabling mental illness with the core symptoms of obsession and compulsion, while its pathological mechanism has not yet been fully understood. In recent years, magnetic resonance (MR) technology has been used in the study of mental illness, because of its nonradiative and non-invasive advantage, etc. Many MR studies have found that OCD patients have cerebellar changes in structure and function, and these changes have contact with the incidence of OCD. This paper reviews the cerebellar’s role in the onset of OCD applying MR technology.

Key words: obsessive compulsive disorder, cerebellum, magnetic resonance, diffusion tensor image