上海交通大学学报（医学版）

上海交通大学学报（医学版）

• 论著（临床研究） • 上一篇    下一篇

视觉P300电位在精神分裂症司法鉴定责任能力评定中的初步应用

韩慧琴1，谢 斌1，穆俊林2，杨晓敏1，张明岛1，楼翡璎1，梁建华1，陈 冲1   

  1. 1.上海交通大学 医学院附属精神卫生中心， 上海 200030； 2.河南省精神病医院， 郑州 453002
  • 出版日期:2014-01-28 发布日期:2014-01-29
  • 通讯作者: 谢 斌, 电子信箱: binxie64@gmail.com。
  • 作者简介:韩慧琴（1982—）， 女， 住院医师， 硕士; 电子信箱: hhq04172005@163.com。
  • 基金资助:

    上海市精神卫生中心院级课题（2011YJ09）；科技部“十二五”科技支撑计划（2012BAK16B04）；国家自然科学基金青年项目（81202388）

Preliminary study on application of visual P300 potentials in responsible appreciation of schizophrenia patients by judicial expertise

HAN Hui-qin1, XIE Bin1, MU Jun-lin2, YANG Xiao-min1, ZHANG Ming-dao1, LOU Fei-ying1, LIANG Jian-hua1, CHEN Chong1   

  1. 1．Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China； 2．Henan Provincial Mental Hospital, Zhengzhou 453002, China
  • Online:2014-01-28 Published:2014-01-29
  • Supported by:

    Foundation of Shanghai Mental Health Center, 2011-YJ-09; Major Science and Technology Support Program of Ministry of Science and Technology in the National “12th 5-year Plan” of China, 2012BAK16B04; Young Scientists Project of National Natural Science Foundation of China, 81202388

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摘要：

目的 探讨视觉P300在精神分裂症司法鉴定责任能力评定中的价值。方法 分别对经司法鉴定为无责任能力的精神分裂症患者（n=68，无责任能力组）和限定责任能力的精神分裂症患者（n=59，限定责任能力组）进行视觉司法事件相关脑电位P300检测，以58名志愿受试者作为对照（正常组）。结果 与正常组比较，无责任能力组和限定责任能力组P300 电位成分中N1、N2和P3潜伏期显著延长（P<0.01），P3波幅显著降低（P<0.01）。无责任能力组P300电位成分中N1、N2和P3潜伏期较限定责任能力组显著延长，P3波幅则显著降低，组间比较差异均有统计学意义（P<0.01）。结论 视觉P300在精神分裂症司法鉴定责任能力评定中有一定的参考意义，但研究结果还有待进一步随访验证。

关键词: 司法鉴定, 责任能力, 精神分裂症, 视觉P300电位

Abstract:

Objective To explore the value of visual P300 potentials in responsible appreciation of schizophrenia patients by judicial expertise. Methods Sixty-eight schizophrenia patients without responsible ability (group A) and 59 schizophrenia patients with limited responsible ability (group B) by judicial expertise and 58 healthy volunteers (group C) were enrolled in this study. They were given visual P300 potentials test. Results Compared to group C, latent periods of N1, N2, and P3 of P300 in groups A and B were significantly longer (P<0.01), and the amplitude of P3 decreased markedly (P<0.01). Compared to group B, latent periods of N1, N2, and P3 of P300 in group A were significantly longer, and amplitude of P3 decreased markedly (P<0.01). Conclusion Visual P300 potentials test has referential meaning in responsible appreciation of schizophrenia by judicial expertise, which needs confirmation by long follow-up.

Key words: judicial expertise, responsible ability, schizophrenia, visual P300 potentials