上海交通大学学报（医学版）

上海交通大学学报（医学版）

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围绝经期女性睡眠障碍的研究进展

郑燕伟，陶敏芳   

  1. 上海交通大学附属第六人民医院妇产科， 上海 200233
  • 出版日期:2016-07-28 发布日期:2016-08-31
  • 通讯作者: 陶敏芳, 电子信箱: taomf@sjtu.com。
  • 作者简介:郑燕伟（1988—）， 女， 硕士生; 电子信箱: ywzheng2011@163.com。
  • 基金资助:

    上海市科委基金（15411950202）

Research progresses of sleep disorder in perimenopausal women

ZHENG Yan-wei, TAO Min-fang   

  1. Department of Obstetrics and Gynecology, Shanghai Sixth Peoples Hospital, Shanghai Jiao Tong University, Shanghai 200233， China
  • Online:2016-07-28 Published:2016-08-31
  • Supported by:

    Shanghai Committee of Science and Technology Fundation, 15411950202

PDF (PC)

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摘要：

睡眠障碍是围绝经期女性的常见症状之一，主要表现为入睡困难、夜间觉醒次数增多、晨间早醒、醒后无法再入睡等，其原因可能与该时期出现的雌激素水平变化及其变化所导致的血管舒缩症状、情绪障碍等有关。绝经相关的睡眠障碍发生率受人种、遗传因素、环境因素以及患慢性疾病和药物治疗等情况的影响差异较大。绝经睡眠障碍治疗包括一般治疗和药物治疗，其中激素替代治疗有一定的疗效。该文就围绝经期女性睡眠障碍的流行病学研究、诱导因素及干预治疗进展等进行综述。

关键词: 围绝经期, 睡眠障碍, 激素替代治疗

Abstract:

Sleep disorder is one of common symptoms in perimenopausal women with major manifestations of difficulty sleeping, frequently waking up at night, early morning waking up, and unable to fall asleep after waking up, which may be related to oestrogen level changes in this period and resulting in vasomotor symptoms and mood disorders. The incidence of sleep disorder related to menopause is greatly affected by race, genetic factors, environmental factors, chronic diseases, and medications, etc. The treatments of menopausal sleep disorder include general therapy and medications. The hormone replacement therapy has certain efficacy. This article reviews progresses of epidemiological studies, inducing factors, and intervention treatments of sleep disorder in perimenopausal women.

Key words: perimenopausal, sleep disorder, hormone replacement therapy