上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2018, Vol. 38 ›› Issue (11): 1349-.doi: 10.3969/j.issn.1674-8115.2018.11.014

• 论著·临床研究 • 上一篇    下一篇

经皮氧饱和度测定结合心脏超声远程会诊筛查新生儿危重先天性心脏病

沈奕 1，赵莉晴 2，刘晓青 1，郁燕 1，刘岚 1，武育蓉 2   

  1. 1. 上海交通大学医学院附属新华医院崇明分院儿科，上海 202150；2. 上海交通大学医学院附属新华医院小儿心血管科，上海 200092
  • 出版日期:2018-11-28 发布日期:2018-12-15
  • 作者简介:沈奕 (1983—)，女，住院医师，学士；电子信箱： tao15021859895@163.com。
  • 基金资助:
    2011年新华医院重点扶植学科；上海交通大学医工交叉项目（ YG2015MS70）

Percutaneous oxygen saturation measurement combined with echocardiography remote consultation in screening of neonatal critical congenital heart disease

SHEN Yi1, ZHAO Li-qing2, LIU Xiao-qing1, YU Yan1, LIU Lan1, WU Yu-rong2   

  1. 1. Department of Paediatrics, Xinhua Hospital Chongming Branch, Shanghai Jiao Tong University School of Medicine, Shanghai 202150, China; 2. Department of Pediatric Cardiovascular, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
  • Online:2018-11-28 Published:2018-12-15
  • Supported by:
    Key Discipline of Xinhua Hospital, Shanghai Jiao Tong Univerisity School of Medicine；Biomedical Engineering Cross Foundation of Shanghai Jiao Tong University,YG2015MS70

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摘要： 目的 ·探讨经皮氧饱和度测定结合心脏超声远程会诊在偏远地区新生儿危重型先天性心脏病（ critical congenital heart disease， CCHD）筛查及转诊中的价值。方法 ·以上海崇明区 2014—2016年的活产新生儿为筛检对象，于生后 24～ 48 h进行经皮氧饱和度测定筛检 CCHD，同时按照先天性心脏病分段诊断方法录制标准切面，将心脏超声图像通过微信平台远程会诊后进行初步确诊。结果 ·共 4 450例活产新生儿接受筛检，阳性 11例，经心脏超声远程会诊初步确诊 CCHD 6例，筛检阴性者中 1例后经心脏超声诊断为肺动脉闭锁伴室间隔缺损。经皮氧饱和度筛检 CCHD的敏感度为 85.71%，特异度为 99.89%，假阳性率为 0.11%，假阴性率为 14.29%，ROC曲线下面积为 0.928。结论 ·经皮氧饱和度测定可以有效筛查出 CCHD，结合微信平台心脏超声远程会诊可以初步确诊 CCHD，既可及时转诊，又可避免不必要的转诊。该筛查模式简便易行，在缺少先天性心脏病诊治专业医技人员的偏远地区有实用价值。

关键词: 先天性心脏病, 氧饱和度, 筛查, 心脏超声, 远程会诊

Abstract:

Objective · To investigate the value of percutaneous oxygen saturation measurement combined with echocardiography remote consultation in the screening and referral of neonatal critical congenital heart disease (CCHD) in remote areas. Methods · The live newborns who were born between 2014 and 2016 in Chongming District of Shanghai were taken as the objects of study, the percutaneous oxygen saturation was measured at 24-48 h after birth. The data were classified according to congenital heart disease segmental diagnosis standard in the mean time, and the echocardiography was preliminary diagnosed after the remote consultation through WeChat platform. Results · A total of 4 450 live newborns were screened, 11 cases were positive, 6 cases were preliminary diagnosed as CCHDthe echocardiography remote consultation, and 1 case of negative screening was later diagnosed as pulmonary atresia with ventricular septal defectechocardiography. The sensitivity of percutaneous oxygen saturation screening for CCHD was 85.71%, the specificity was 99.89%, the false positive rate was 0.11%, the false negative rate was 14.29%, and the area under the ROC curve was 0.928. Conclusion · CCHD can be screened out effectivelypercutaneous oxygen saturation combined with the WeChat platform, and it can be preliminary diagnosedthe echocardiography remote consultation, which can provide timely referral and avoid unnecessary referral. This screening model is simple and practical. It has practical value in remote areasare lack of professional medical technicians for the diagnosis and treatment of congenital heart disease.

Key words: congenital heart disease, oxygen saturation, screening, echocardiography, remote consultation

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