上海交通大学学报(医学版) ›› 2020, Vol. 40 ›› Issue (05): 646-650.doi: 10.3969/j.issn.1674-8115.2020.05.013

• 论著·临床研究 • 上一篇    下一篇

18F-FDG PET/CT引导下穿刺活检在腹膜增厚性疾病良恶性鉴别中的应用

王海岩,尤志雯,寿 毅,孟庆元,陈慧倩,赵 军   

  1. 同济大学附属东方医院核医学科,上海 200120
  • 出版日期:2020-05-28 发布日期:2020-05-28
  • 通讯作者: 赵 军,电子信箱:petcenter@126.com。
  • 作者简介:王海岩(1976—),女,主治医师,硕士;电子信箱:13816707601@163.com。
  • 基金资助:
    上海市科学技术委员会项目(19DZ1930703);上海市浦东新区卫生系统重点专科建设项目(PWZzk2017-24)。

Application of 18F-FDG PET/CT-guided percutaneous biopsy to differential diagnosis of peritoneal thickening diseases

WANG Hai-yan, YOU Zhi-wen, SHOU Yi, MENG Qing-yuan, CHEN Hui-qian, ZHAO Jun   

  1. Department of Nuclear Medicine, Shanghai East Hospital, Tongji University, Shanghai 200120, China
  • Online:2020-05-28 Published:2020-05-28
  • Supported by:
    Project of Science and Technology Commission of Shanghai Municipality (19DZ1930703); Key Specialty Construction Project of Pudong Health and Family Planning Commission of Shanghai (PWZzk2017-24).

摘要: 目的·探讨18F-氟脱氧葡萄糖(18F-flurodeoxyglucose,18F-FDG)正电子发射计算机断层/X线计算机体层摄影(positron emission tomography/computed tomography,PET/CT)引导下经皮腹膜穿刺活检在腹膜增厚性疾病良恶性鉴别中的应用价值。方法·回顾性分析10例腹膜增厚原因待查患者,其中男4例,女6例;18F-FDG PET/CT检查发现腹膜病变,选择18F-FDG代谢活性较高的靶区,在同机PET/CT引导下经皮腹膜穿刺活检。结果·所有病例均一次性穿刺取材成功,无严重并发症,均取得组织病理学诊断结果。7例腹膜穿刺病理诊断为恶性病变,包括4例腹膜转移肿瘤、3例淋巴瘤;余下的3例分别为1例腹膜假黏液瘤、1例结核病变、1例炎症病变。穿刺活检准确率为100%。结论·18F-FDG PET/CT引导下经皮腹膜穿刺活检是一种安全、有效的方法,在腹膜增厚性疾病的良恶性鉴别诊断和治疗决策中发挥重要作用。

关键词: 腹膜, 穿刺活检术, 正电子发射计算机断层/X线计算机体层摄影, 18F-氟脱氧葡萄糖

Abstract:

Objective · To investigate the clinical value of 18F-flurodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) -guided percutaneous biopsy in peritoneal thickening of unknown origin. Methods · Ten cases of peritoneal thicken of unknown origin including 4 males and 6 females were analyzed. After 18F-FDG PET/CT examination, the peritoneal thickening regions with high 18F-FDG uptake were selected for the target areas. Percutaneous biopsy was operated under the guidance of the same PET/CT machine. Results · All lesions were successfully obtained by one-time puncture without serious complications, and histopathological diagnosis revealed that 7 cases were malignant, including 4 cases of peritoneal metastasis and 3 cases of lymphoma. The remaining cases were 1 case of pseudomyxoma, 1 case of tuberculosis and 1 case of inflammatory lesions. The accuracy of biopsy was 100%. Conclusion · 18F-FDG PET/CT-guided peritoneal percutaneous biopsy is a safe and effective method, and may play an important role in differential diagnosis and treatment management.

Key words: peritoneum, percutaneous biopsy, positron emission tomography/computed tomography (PET/CT), 18F-flurodeoxyglucose (18F-FDG)

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