音乐治疗缓解激越状态的研究进展

doi:10.3969/j.issn.1674-8115.2026.01.012

上海交通大学学报（医学版） ›› 2026, Vol. 46 ›› Issue (1): 100-106.doi: 10.3969/j.issn.1674-8115.2026.01.012

• 综述 • 上一篇

音乐治疗缓解激越状态的研究进展

杨品纬, 陈依明, 洪武()

上海交通大学医学院附属精神卫生中心临床六科，上海 200030

收稿日期:2025-04-15 接受日期:2025-10-20 出版日期:2026-01-28 发布日期:2026-01-30
通讯作者: 洪　武，主任医师，博士；电子信箱：drhongwu@126.com。
作者简介:第一联系人：杨品纬负责论文撰写，陈依明负责论文撰写的指导，洪武对研究给予指导。所有作者均阅读并同意了最终稿件的提交。
基金资助:
国家科技创新2030“脑科学与类脑研究”重大项目(2021ZD0200800);上海市“科技创新行动计划”医学创新研究专项(21Y11905600);上海市精神卫生中心研究型医师培养和能力提升计划(2021-YJXYS-06)

Advances in music therapy for the treatment of agitation

Yang Vivien, Chen Yiming, Hong Wu()

Sixth Clinical Department, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China

Received:2025-04-15 Accepted:2025-10-20 Online:2026-01-28 Published:2026-01-30
Contact: Hong Wu, E-mail: drhongwu@126.com.
About author:First author contact:Yang Vivien was responsible for manuscript writing. Chen Yiming provided guidance on manuscript revision. Hong Wu provided research supervision. All authors have read the last version of paper and consented to its submission.
Supported by:
National Science and Technology Innovation 2030-Major Project of Brain Science and Brain-like Research(2021ZD0200800);Shanghai“Science and Technology Innovation Action Plan”Medical Innovation Research(21Y11905600);Research-Oriented Physician Training and Capacity-Building Program of Shanghai Mental Health Center(2021-YJXYS-06)

摘要/Abstract

摘要：

激越状态是精神科临床中常见的症状之一，通常伴随情绪波动、攻击性行为等，严重影响患者的治疗进程，并对医护人员的安全构成威胁。前额叶功能异常和多种神经递质紊乱被认为是激越发生的主要生物学机制。音乐治疗作为一种非药物干预手段，能够通过激活大脑功能连接、调节神经递质活动及生理应激反应，显著缓解激越状态。此外，音乐治疗在阿尔茨海默病、创伤性脑损伤、精神分裂症等特定精神疾病患者中的临床应用展现了积极的疗效。未来的研究应进一步聚焦于揭示音乐治疗缓解激越状态的神经生物学机制，探索多模态干预的结合应用，以及评估其长期疗效，以推动其在临床实践中的广泛应用和持续优化。

关键词: 音乐治疗, 激越, 情绪调节, 精神障碍

Abstract:

Agitation is a common symptom in psychiatric clinical practice, typically accompanied by emotional fluctuations and aggressive behaviors, which significantly impair patients′ treatment outcomes and pose safety risks to healthcare providers. Abnormal prefrontal cortex function and various neurotransmitter imbalances are considered the primary biological mechanisms underlying the onset of agitation. Music therapy, as a non-pharmacological intervention, has been shown to effectively alleviate agitation by enhancing brain functional connectivity, modulating neurotransmitter activity, and regulating physiological stress responses. Furthermore, music therapy has demonstrated positive therapeutic effects in clinical applications for patients with specific psychiatric conditions, such as Alzheimer′s disease, traumatic brain injury, and schizophrenia. Future research should focus on further elucidating the neurobiological mechanisms by which music therapy mitigates agitation, exploring the integration of multimodal interventions, and evaluating long-term efficacy, in order to facilitate its widespread clinical implementation and continuous optimization.

Key words: music therapy, agitation, emotional accommodation, mental disorder

中图分类号:

R749

杨品纬, 陈依明, 洪武. 音乐治疗缓解激越状态的研究进展[J]. 上海交通大学学报（医学版）, 2026, 46(1): 100-106.

Yang Vivien, Chen Yiming, Hong Wu. Advances in music therapy for the treatment of agitation[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2026, 46(1): 100-106.

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音乐治疗缓解激越状态的研究进展

Advances in music therapy for the treatment of agitation

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