上海交通大学学报（医学版）

›› 2013, Vol. 33 ›› Issue (1): 71-.doi: 10.3969/j.issn.1674-8115.2013.01.014

• 论著（临床研究） • 上一篇    下一篇

EmbryoGlue移植液对胚胎移植后临床结局的影响

张建瑞1, 管一春1, 章露文2, 郝大勇1, 王雪梅1, 刘 景1, 王兴玲1   

  1. 1.郑州大学 第三附属医院生殖医学中心, 郑州 450052； 2.郑州人民医院营养科, 郑州 450052
  • 出版日期:2013-01-28 发布日期:2013-02-06
  • 作者简介:张建瑞（1983—）, 男, 硕士；电子信箱: aixinjiaren@163.com。

Influence of transfer medium EmbryoGlue on clinical outcome of embryo transfer

ZHANG Jian-rui1, GUAN Yi-chun1, ZHANG Lu-wen2, HAO Da-yong1, WANG Xue-mei1, LIU Jing1, WANG Xing-ling1   

  1. 1.Center for Reproductive Medicine, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China； 2. Department of Nutrition, People´s Hospital of Zhengzhou, Zhengzhou 450052, China
  • Online:2013-01-28 Published:2013-02-06

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摘要：

目的 探讨EmbryoGlue移植液对体外受精-胚胎移植（IVF-ET）患者临床妊娠率的影响。方法 选取接受IVF-ET治疗的患者为研究对象，采用EmbryoGlue作为移植液的共232周期（EmbryoGlue组），采用G-2作为移植液的共268周期（G-2组），比较两组患者的临床参数和妊娠结局。结果 两组患者的年龄、不孕年限、既往失败周期数、子宫内膜厚度、优质胚胎数和平均移植胚胎数比较，差异均无统计学意义（P>0.05）。EmbryoGlue组的临床妊娠率、胚胎种植率、多胎妊娠率明显高于G-2组，差异有统计学意义（P<0.05）；EmbryoGlue组的宫外孕发生率明显低于G-2组，差异有统计学意义（P<0.05）。结论 使用EmbryoGlue作为移植液可以提高IVF-ET的妊娠率和种植率。

关键词: EmbryoGlue移植液, 体外受精-胚胎移植, 妊娠结局

Abstract:

Objective To investigate the influence of transfer medium EmbryoGlue on pregnancy outcome of in vitro fertilization-embryo transfer (IVF-ET). Methods Patients undergoing IVF-ET were enrolled, and were divided into EmbryoGlue group (EmbryoGlue as transfer medium, 232 cycles) and G-2 group (G-2 as transfer medium, 268 cycles). The clinical parameters and pregnancy outcomes were compared between groups. Results There was no significant difference in the age, duration of infertility, number of unsuccessful cycles, thickness of endometrium, number of good quality embryo, mean number of embryo transfer between groups (P>0.05). The clinical pregnancy rate, implantation rate, multiple pregnancy rate in EmbryoGlue group were significantly higher than those in G-2 group (P<0.05). The prevalence of ectopic pregnancy in EmbryoGlue group was significantly lower than that in G-2 group (P<0.05). Conclusion As an embryo transfer medium, EmbryoGlue can improve the pregnancy rate and implantation rate of IVF-ET.

Key words: EmbryoGlue, in vitro fertilization-embryo transfer, pregnancy outcome