›› 2010, Vol. 30 ›› Issue (9): 1039-.doi: 10.3969/j.issn.1674-8115.2010.09.005

• Monographic report (Medical imaging and nuclear medicine) • Previous Articles     Next Articles

Clinical application of 18F-FDG PET/CT in detection of primary tumors of multiple bone metastatic tumors

CHEN Gang, |ZHANG Miao, |HU Jia-jia, |JIANG Xu-feng, |WANG Chao, |LI Biao   

  1. Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2010-09-25 Published:2010-09-27
  • Supported by:

    Shanghai Leading Academic Discipline Project, S30203

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Abstract:

Objective To explore the clinical application of 18F-FDG PET/CT in detection of primary tumors of multiple bone metastatic tumors. Methods The results of detection of primary tumors by 18F-FDG PET/CT in 77 patients with multiple bone metastatic tumors were retrospectively analysed, and comparisons were conducted with pathological findings. Results In all the 77 patients, 18F-FDG PET/CT revealed 44 suspected primary tumors, among whom 40 were confirmed by surgical or pathological examinations, and the other 4 were false positive cases. In the 37 patients without primary tumors detected by 18F-FDG PET/CT, one was diagnosed as gastric Signet ring cell carcinoma by pathological examination after operation, and primary tumors were not found in the other 36 patients during the follow up. The sensitivity, specificity and accuracy of 18F-FDG PET/CT in detection of primary tumors were 97.6%, 88.9% and 93.5%, respectively. Conclusion 18F-FDG PET/CT has definite value in detection of primary tumors of multiple bone metastatic tumors.

Key words: bone metastatic tumor, primary tumor, PET, radionuclide imaging