›› 2010, Vol. 30 ›› Issue (9): 1164-.doi: 10.3969/j.issn.1674-8115.2010.09.035

• Review • Previous Articles     Next Articles

Research progress of vascular protection mechanism of adiponectin

ZHANG Ling-juan, reviewer;SU Qing, reviser   

  1. Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
  • Online:2010-09-25 Published:2010-09-27

Abstract:

Adiponectin is an abundant plasma protein secreted from adipocytes that elicits protective effects in the vasculature and myocardium. Adiponectin suppresses oxidative stress, inhibits inflammatory signaling cascades, ameliorates microvascular circulation and regulates angiogenesis via multiple signal pathways. The research progress of vascular protection mechanism of adiponectin is reviewed in this paper.

Key words: adiponectin, atherosclerosis, signal pathway