Journal of Shanghai Jiao Tong University (Medical Science) ›› 2022, Vol. 42 ›› Issue (5): 685-689.doi: 10.3969/j.issn.1674-8115.2022.05.019

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Research progress of fractional CO2 laser therapy in female stress urinary incontinence

DENG Lu(), LI Jiayi()   

  1. Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
  • Received:2021-01-17 Accepted:2022-05-13 Online:2022-05-28 Published:2022-05-28
  • Contact: LI Jiayi;


Stress urinary incontinence (SUI) is common in middle-aged and elderly women, and its incidence is also rising with the growth of aging population. Clinically, the main first-line treatment for mild to moderate SUI is pelvic floor muscle training, but it requires a lot of time and attention from both doctors and patients. In recent years, more and more studies have been conducted to explore the laser treatment of SUI, and the feasibility of transvaginal fractional CO2 laser treatment for SUI has been preliminarily confirmed. Fractional CO2 laser can rapidly promote the proliferation of elastic fiber and collagen in the fractional photothermal area, and increase the thickness and elasticity of urethra supporting structure, thus increasing the stability of urethra and improving control of urination. However, most clinical studies in this field are non-randomized trials with small samples, and it is not yet possible to draw effective conclusions on its efficacy and safety. This paper reviews the specific mechanism and clinical research progress of fractional CO2 laser in the treatment of female SUI, and provides theoretical basis and clinical evidence reference for the application of this therapy.

Key words: stress urinary incontinence (SUI), CO2 laser, treatment effect, safety

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