Journal of Shanghai Jiao Tong University (Medical Science) ›› 2022, Vol. 42 ›› Issue (3): 357-363.doi: 10.3969/j.issn.1674-8115.2022.03.014
• Evidence-based medicine • Previous Articles Next Articles
LI Yan1(), JIANG Yan2, KANG Qiongfang3, LU Qunfeng2()
Received:
2021-10-15
Online:
2022-03-28
Published:
2022-05-09
Contact:
LU Qunfeng
E-mail:ncdwwll@126.com;luluroom2004@163.com
CLC Number:
LI Yan, JIANG Yan, KANG Qiongfang, LU Qunfeng. Summary of the best evidence summary on prevention strategies for diaper dermatitis in infants[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2022, 42(3): 357-363.
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URL: https://xuebao.shsmu.edu.cn/EN/10.3969/j.issn.1674-8115.2022.03.014
Study | Year | Resource | Type | Theme |
---|---|---|---|---|
MATHEW[ | 2021 | JBI | Evidence summary | Management of diaper dermatitis in infants and preschool children |
BAER[ | 2006 | Cochrane | Systematic review | Application of disposable diapers in prevention of infant diaper dermatitis |
DAVIES[ | 2005 | Cochrane | Systematic review | Role of topical vitamin A or its derivatives in the treatment and prevention of infant diaper dermatitis |
ROWE[ | 2008 | JBI | Systematic review | Effect of barrier preparation on prevention/treatment of diaper dermatitis in infants and preschool children |
BLUME-PEYTAVI[ | 2014 | DARE | Systematic review | Prevention of diaper dermatitis in infant: a literature review |
ZHANG[ | 2020 | Medlive | Consensus approach | Expert consensus on nursing practice of infant diaper dermatitis |
HORII[ | 2019 | UptoDate | Clinical decision | Clinical decision making in the management of diaper dermatitis |
BMJ[ | 2018 | Best Practice | Clinical decision | An overview of dermatitis |
Tab 1 Characteristics of included studies
Study | Year | Resource | Type | Theme |
---|---|---|---|---|
MATHEW[ | 2021 | JBI | Evidence summary | Management of diaper dermatitis in infants and preschool children |
BAER[ | 2006 | Cochrane | Systematic review | Application of disposable diapers in prevention of infant diaper dermatitis |
DAVIES[ | 2005 | Cochrane | Systematic review | Role of topical vitamin A or its derivatives in the treatment and prevention of infant diaper dermatitis |
ROWE[ | 2008 | JBI | Systematic review | Effect of barrier preparation on prevention/treatment of diaper dermatitis in infants and preschool children |
BLUME-PEYTAVI[ | 2014 | DARE | Systematic review | Prevention of diaper dermatitis in infant: a literature review |
ZHANG[ | 2020 | Medlive | Consensus approach | Expert consensus on nursing practice of infant diaper dermatitis |
HORII[ | 2019 | UptoDate | Clinical decision | Clinical decision making in the management of diaper dermatitis |
BMJ[ | 2018 | Best Practice | Clinical decision | An overview of dermatitis |
Study | Q1 | Q2 | Q3 | Q4 | Q5 | Q6 | Q7 | Q8 | Q9 | Q10 | Q11 | Q12 | Q13 | Q14 | Q15 | Q16 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BAER[ | Y | Y | Y | Y | Y | Y | Y | P | Y | Y | Y | Y | Y | N | Y | Y |
DAVIES[ | Y | Y | Y | Y | Y | Y | P | Y | Y | N | Y | Y | Y | N | Y | Y |
ROWE[ | Y | Y | Y | Y | Y | Y | Y | Y | Y | N | Y | Y | Y | N | Y | Y |
BLUME-PEYTAVI[ | Y | N | Y | Y | Y | N | Y | Y | Y | N | Y | Y | Y | N | N | N |
Tab 2 Quality evaluation of systematic reviews
Study | Q1 | Q2 | Q3 | Q4 | Q5 | Q6 | Q7 | Q8 | Q9 | Q10 | Q11 | Q12 | Q13 | Q14 | Q15 | Q16 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BAER[ | Y | Y | Y | Y | Y | Y | Y | P | Y | Y | Y | Y | Y | N | Y | Y |
DAVIES[ | Y | Y | Y | Y | Y | Y | P | Y | Y | N | Y | Y | Y | N | Y | Y |
ROWE[ | Y | Y | Y | Y | Y | Y | Y | Y | Y | N | Y | Y | Y | N | Y | Y |
BLUME-PEYTAVI[ | Y | N | Y | Y | Y | N | Y | Y | Y | N | Y | Y | Y | N | N | N |
Evaluation criterion | Result | |
---|---|---|
LI[ | ADALAT[ | |
1. Whether the inclusion criteria of the sample are clearly defined | Y | N |
2. Whether the research object and the research site are described in detail | Y | Y |
3. Whether the measurement method of exposure factors has reliability and validity | Y | N/C |
4. Whether diseases or health problems are defined by objective and consistent criteria | Y | Y |
5. Whether confounding factors are identified | N | N |
6. Whether measures are taken to control confounding factors | N | N |
7. Whether the measurement method of outcome index has reliability and validity | Y | Y |
8. Whether the data analysis methods are appropriate | Y | Y |
Tab 3 Evaluation of cross-sectional studies
Evaluation criterion | Result | |
---|---|---|
LI[ | ADALAT[ | |
1. Whether the inclusion criteria of the sample are clearly defined | Y | N |
2. Whether the research object and the research site are described in detail | Y | Y |
3. Whether the measurement method of exposure factors has reliability and validity | Y | N/C |
4. Whether diseases or health problems are defined by objective and consistent criteria | Y | Y |
5. Whether confounding factors are identified | N | N |
6. Whether measures are taken to control confounding factors | N | N |
7. Whether the measurement method of outcome index has reliability and validity | Y | Y |
8. Whether the data analysis methods are appropriate | Y | Y |
Prevention strategy | Evidence | Grade |
---|---|---|
Air | 1. There should be a period of nappy-free time each day[ | Ⅴb |
Barrier | 2. Apply protectant at each diaper change to protect skin from irritants, such as urine and feces[ | Ⅰc |
3. It is better to choose a barrier preparation or medicine for external usage with the fewest ingredients, avoiding irritating or allergenic ingredients, such as aromatic agent, preservative, neomycin, boric acid, camphor, phenol, benzocaine and salicylate. Otherwise, it may result in systemic toxicity or methemoglobinemia[ | Ⅰc | |
4. Pastes and ointments are usually better than creams and lotions; the adhesion of creams and emulsions is poor and the sealing degree is very low. They often contain aromatics and preservatives as well[ | Ⅰb | |
5. Sucralfate can also act as a physical barrier against irritants. It has antibacterial activity, which is useful in the treatment of severe or intractable irritant diaper dermatitis[ | Ⅳd | |
6. Olive oil and marigold ointment have similar effect on preventing diaper-related dermatitis[ | Ⅰc | |
7. The effect of vitamin A in the prevention of diaper dermatitis is unclear[ | Ⅰc | |
Cleaning | 8. Dry manure can be gently removed by dipping a cotton ball in paraffin oil[ | Ⅴc |
9. Barrier paste doesn’t need to be completely removed at each diaper change, and paraffin oil can be used to assist when necessary[ | Ⅰa | |
10. Excessive use of cleaners and excessive friction should be avoided[ | ||
11. Warm water (37‒40 ℃) and soft cloth can be used to clean the skin, and baby wipes with the least additive and no aromatic agent, ethanol, fluorescent agent, dyes, and preservatives can be chosen. You should scrub and pat gently on the undamaged skin[ | Ⅰa | |
12. Baby wipes should be discontinued if irritation or breakage occurs[ | Ⅴc | |
13. The diaper area should be cleaned with a small amount of a gentle cleanser with a physiological pH[ | Ⅴc | |
14. In preterm and term newborns, the use of wipe will reduce skin pH value, percutaneous moisture loss and less skin erythema[ | Ⅰc | |
15. A separate baby bath should be used to reduce diaper red spots and rough, dry skin[ | Ⅰc | |
16. In the case of bathing twice a week, bathing with water alone can improve newborn skin conditions and reduce the incidence of nappy-related dermatitis compared to bathing with water and body gel[ | Ⅰc | |
Diaper | 17. Disposable diapers are recommended[ | Ⅰa |
18. Nappies with hydroscopicity gel are superior to cellulose core nappies, cellulose core diapers are better than cloth diapers, air permeable nappies are superior to air tight nappies, and diapers with permeability stains are better than regular diapers[ | Ⅰa | |
19. Using plastic underwear over diapers should be avoided[ | Ⅴc | |
20. Diapers should at suitable size and tightness[ | Ⅴb | |
21. If the baby is allergic to diapers, a different brand or a soft cotton diaper should be chosen[ | Ⅴb | |
22. Frequent diaper changes are effective measures to prevent diaper dermatitis[ | Ⅰa | |
23. Diapers should be changed every 2 h (or checked for soiled at least every 2 h), and newborns and children with diarrhea should be changed more frequently [ | Ⅴb | |
24. Diapers after defecation immediately should be changed[ | Ⅴb | |
25. The diaper should be replaced 1 h after diuretic application[ | Ⅴb | |
Education | 26. Parents and healthcare personnel should be educated on appropriate exposure, selection of barrier agents, skin cleaning, diaper selection, and timing of diaper change[ | Ⅴb |
Tab 4 Summary of the best evidence on risk screening and prevention strategies for diaper dermatitis in infants
Prevention strategy | Evidence | Grade |
---|---|---|
Air | 1. There should be a period of nappy-free time each day[ | Ⅴb |
Barrier | 2. Apply protectant at each diaper change to protect skin from irritants, such as urine and feces[ | Ⅰc |
3. It is better to choose a barrier preparation or medicine for external usage with the fewest ingredients, avoiding irritating or allergenic ingredients, such as aromatic agent, preservative, neomycin, boric acid, camphor, phenol, benzocaine and salicylate. Otherwise, it may result in systemic toxicity or methemoglobinemia[ | Ⅰc | |
4. Pastes and ointments are usually better than creams and lotions; the adhesion of creams and emulsions is poor and the sealing degree is very low. They often contain aromatics and preservatives as well[ | Ⅰb | |
5. Sucralfate can also act as a physical barrier against irritants. It has antibacterial activity, which is useful in the treatment of severe or intractable irritant diaper dermatitis[ | Ⅳd | |
6. Olive oil and marigold ointment have similar effect on preventing diaper-related dermatitis[ | Ⅰc | |
7. The effect of vitamin A in the prevention of diaper dermatitis is unclear[ | Ⅰc | |
Cleaning | 8. Dry manure can be gently removed by dipping a cotton ball in paraffin oil[ | Ⅴc |
9. Barrier paste doesn’t need to be completely removed at each diaper change, and paraffin oil can be used to assist when necessary[ | Ⅰa | |
10. Excessive use of cleaners and excessive friction should be avoided[ | ||
11. Warm water (37‒40 ℃) and soft cloth can be used to clean the skin, and baby wipes with the least additive and no aromatic agent, ethanol, fluorescent agent, dyes, and preservatives can be chosen. You should scrub and pat gently on the undamaged skin[ | Ⅰa | |
12. Baby wipes should be discontinued if irritation or breakage occurs[ | Ⅴc | |
13. The diaper area should be cleaned with a small amount of a gentle cleanser with a physiological pH[ | Ⅴc | |
14. In preterm and term newborns, the use of wipe will reduce skin pH value, percutaneous moisture loss and less skin erythema[ | Ⅰc | |
15. A separate baby bath should be used to reduce diaper red spots and rough, dry skin[ | Ⅰc | |
16. In the case of bathing twice a week, bathing with water alone can improve newborn skin conditions and reduce the incidence of nappy-related dermatitis compared to bathing with water and body gel[ | Ⅰc | |
Diaper | 17. Disposable diapers are recommended[ | Ⅰa |
18. Nappies with hydroscopicity gel are superior to cellulose core nappies, cellulose core diapers are better than cloth diapers, air permeable nappies are superior to air tight nappies, and diapers with permeability stains are better than regular diapers[ | Ⅰa | |
19. Using plastic underwear over diapers should be avoided[ | Ⅴc | |
20. Diapers should at suitable size and tightness[ | Ⅴb | |
21. If the baby is allergic to diapers, a different brand or a soft cotton diaper should be chosen[ | Ⅴb | |
22. Frequent diaper changes are effective measures to prevent diaper dermatitis[ | Ⅰa | |
23. Diapers should be changed every 2 h (or checked for soiled at least every 2 h), and newborns and children with diarrhea should be changed more frequently [ | Ⅴb | |
24. Diapers after defecation immediately should be changed[ | Ⅴb | |
25. The diaper should be replaced 1 h after diuretic application[ | Ⅴb | |
Education | 26. Parents and healthcare personnel should be educated on appropriate exposure, selection of barrier agents, skin cleaning, diaper selection, and timing of diaper change[ | Ⅴb |
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