Journal of Shanghai Jiao Tong University (Medical Science) ›› 2023, Vol. 43 ›› Issue (8): 988-996.doi: 10.3969/j.issn.1674-8115.2023.08.006
• Basic research • Previous Articles Next Articles
GAO Nan(), HAO Gem, MA Bingjie, JIN Tian, MA Ke, LIU Xiaoming(
)
Received:
2023-02-14
Accepted:
2023-05-25
Online:
2023-08-28
Published:
2023-08-28
Contact:
LIU Xiaoming
E-mail:gao_n@139.com;brightlxm@qq.com
Supported by:
CLC Number:
GAO Nan, HAO Gem, MA Bingjie, JIN Tian, MA Ke, LIU Xiaoming. Translocator protein activates autophagy in diabetic neuropathic pain rats via regulation of the Keap1/Nrf2/HO-1 signaling[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2023, 43(8): 988-996.
1 | RHEE E J, KIM J H, MOON S J, et al. Encountering COVID-19 as endocrinologists[J]. Endocrinol Metab (Seoul), 2020, 35(2): 197-205. |
2 | FELDMAN E L, CALLAGHAN B C, POP-BUSUI R, et al. Diabetic neuropathy[J]. Nat Rev Dis Primers, 2019, 5: 41. |
3 | GALLUZZI L, GREEN D R. Autophagy-independent functions of the autophagy machinery[J]. Cell, 2019, 177(7): 1682-1699. |
4 | MARTANO M, ALTAMURA G, POWER K, et al. Beclin 1, LC3 and P62 expression in equine sarcoids[J]. Animals, 2021, 12(1): 20. |
5 | CAO W Y, LI J H, YANG K P, et al. An overview of autophagy: mechanism, regulation and research progress[J]. Bull Cancer, 2021, 108(3): 304-322. |
6 | KLIONSKY D J, PETRONI G, AMARAVADI R K, et al. Autophagy in major human diseases[J]. EMBO J, 2021, 40(19): e108863. |
7 | CHUNG Y C, LIM J H, OH H M, et al. Calcimimetic restores diabetic peripheral neuropathy by ameliorating apoptosis and improving autophagy[J]. Cell Death Dis, 2018, 9(12): 1163. |
8 | YU C, XIAO J H. The Keap1-Nrf2 system: a mediator between oxidative stress and aging[J]. Oxid Med Cell Longev, 2021, 2021: 6635460. |
9 | BAIRD L, YAMAMOTO M. The molecular mechanisms regulating the KEAP1-NRF2 pathway[J]. Mol Cell Biol, 2020, 40(13): e00099-e00020. |
10 | LI S, YANG C, FANG X, et al. Role of Keap1-Nrf2 signaling in anhedonia symptoms in a rat model of chronic neuropathic pain: improvement with sulforaphane[J]. Front Pharmacol, 2018, 9: 887. |
11 | FRIAS D P, GOMES R L N, YOSHIZAKI K, et al. Nrf2 positively regulates autophagy antioxidant response in human bronchial epithelial cells exposed to diesel exhaust particles[J]. Sci Rep, 2020, 10(1): 3704. |
12 | RYTER S W. Heme oxygenase-1/carbon monoxide as modulators of autophagy and inflammation[J]. Arch Biochem Biophys, 2019, 678: 108186. |
13 | RUPPRECHT R, WETZEL C H, DOROSTKAR M, et al. Translocator protein (18kDa) TSPO: a new diagnostic or therapeutic target for stress-related disorders?[J]. Mol Psychiatry, 2022, 27(7): 2918-2926. |
14 | HAO C, MA B J, GAO N, et al. Translocator protein (TSPO) alleviates neuropathic pain by activating spinal autophagy and nuclear SIRT1/PGC-1α signaling in a rat L5 SNL model[J]. J Pain Res, 2022, 15: 767-778. |
15 | RASHID K, VERHOYEN M, TAIWO M, et al. Translocator protein (18 kDa) (TSPO) ligands activate Nrf2 signaling and attenuate inflammatory responses and oxidative stress in human retinal pigment epithelial cells[J]. Biochem Biophys Res Commun, 2020, 528(2): 261-268. |
16 | GHEIBI S, KASHFI K, GHASEMI A. A practical guide for induction of type-2 diabetes in rat: incorporating a high-fat diet and streptozotocin[J]. Biomedecine Pharmacother, 2017, 95: 605-613. |
17 | CHAPLAN S R, BACH F W, POGREL J W, et al. Quantitative assessment of tactile allodynia in the rat paw[J]. J Neurosci Methods, 1994, 53(1): 55-63. |
18 | BARRESI E, ROBELLO M, COSTA B, et al. An update into the medicinal chemistry of translocator protein (TSPO) ligands[J]. Eur J Med Chem, 2021, 209: 112924. |
19 | LIU X M, LIU H J, XU S S, et al. Spinal translocator protein alleviates chronic neuropathic pain behavior and modulates spinal astrocyte-neuronal function in rats with L5 spinal nerve ligation model[J]. Pain, 2016, 157(1): 103-116. |
20 | BLOMS-FUNKE P, SCHUMACHER M, LIU S, et al. A novel dual mode-of-action anti-hyperalgesic compound in rats which is neuroprotective and promotes neuroregeneration[J]. Eur J Pharmacol, 2022, 923: 174935. |
21 | MARINELLI S, NAZIO F, TINARI A, et al. Schwann cell autophagy counteracts the onset and chronification of neuropathic pain[J]. Pain, 2014, 155(1): 93-107. |
22 | ARRURI V, KOMIRISHETTY P, ARETI A, et al. Nrf2 and NF-κB modulation by Plumbagin attenuates functional, behavioural and biochemical deficits in rat model of neuropathic pain[J]. Pharmacol Rep, 2017, 69(4): 625-632. |
23 | DI W, SHI X L, LV H, et al. Activation of the nuclear factor E2-related factor 2/anitioxidant response element alleviates the nitroglycerin-induced hyperalgesia in rats[J]. J Headache Pain, 2016, 17(1): 99. |
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