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Advances of relationship between E6/E7 mRNA of human papillomavirus and cervical lesions

ZHANG Sheng-zhi, SHAO Hua-jiang, MA Jian-ting   

  1. Department of Obstetrics & Gynecology, Yangming Hospital affiliated to Medical School of Ningbo University, Yuyao 315400, China
  • Online:2014-05-28 Published:2014-05-30


Human papillomavirus (HPV) is closely related to the occurrence and development of cervical cancer and the expressions of carcinogenic gene E6 and E7 of the virus are the key to the carcinogenesis. When the virus gene integrates into the host, the E6 and E7 gene will be over-expressed and eventually lead to the occurrence of cervical cancer. This paper reviews the research developments of E6 / E7 mRNA, which is the transcription product of E6 and E7 gene.

Key words: human papillomavirus, E6/E7 mRNA, cervical lesions