Journal of Shanghai Jiao Tong University (Medical Science) ›› 2024, Vol. 44 ›› Issue (8): 991-998.doi: 10.3969/j.issn.1674-8115.2024.08.008
• Basic research • Previous Articles Next Articles
LIU Meizhi1(), WANG Ziyang1, JIANG Yaning1, MI Meng2, SUN Yongning1()
Received:
2024-02-08
Accepted:
2024-04-15
Online:
2024-08-28
Published:
2024-08-27
Contact:
SUN Yongning
E-mail:Mary53194@126.com;ynsun2002@126.com
Supported by:
CLC Number:
LIU Meizhi, WANG Ziyang, JIANG Yaning, MI Meng, SUN Yongning. Effects of sennoside A on atherosclerotic plaque formation and expression of 5-hydroxytryptamine signal moleculars in mice with diabetes mellitus type 2[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2024, 44(8): 991-998.
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URL: https://xuebao.shsmu.edu.cn/EN/10.3969/j.issn.1674-8115.2024.08.008
Item | Body weight/g | ||
---|---|---|---|
Control group (n=6) | Model group (n=6) | Model+SA group (n=6) | |
Before treatment | 27.68±1.01 | 29.45±0.54① | 29.53±0.45 |
After treatment | 30.75±1.05 | 33.28±1.04② | 29.92±1.36③ |
Tab 1 Comparison of body weight of mice before and after treatment
Item | Body weight/g | ||
---|---|---|---|
Control group (n=6) | Model group (n=6) | Model+SA group (n=6) | |
Before treatment | 27.68±1.01 | 29.45±0.54① | 29.53±0.45 |
After treatment | 30.75±1.05 | 33.28±1.04② | 29.92±1.36③ |
Item | Control group (n=6) | Model group (n=6) | Model+SA group (n=6) |
---|---|---|---|
Before treatment | |||
FBG/(mmol·L-1) | 4.85±0.55 | 16.87±3.89① | 18.95±4.59 |
PBG/(mmol·L-1) | 6.67±0.77 | 21.53±2.96① | 21.07±2.67 |
After treatment | |||
FBG/(mmol·L-1) | 4.88±1.11 | 21.97±5.33① | 16.12±2.05② |
PBG/(mmol·L-1) | 7.07±0.64 | 25.03±4.29① | 19.60±2.70③ |
Tab 2 Comparison of blood glucose in mice before and after treatment
Item | Control group (n=6) | Model group (n=6) | Model+SA group (n=6) |
---|---|---|---|
Before treatment | |||
FBG/(mmol·L-1) | 4.85±0.55 | 16.87±3.89① | 18.95±4.59 |
PBG/(mmol·L-1) | 6.67±0.77 | 21.53±2.96① | 21.07±2.67 |
After treatment | |||
FBG/(mmol·L-1) | 4.88±1.11 | 21.97±5.33① | 16.12±2.05② |
PBG/(mmol·L-1) | 7.07±0.64 | 25.03±4.29① | 19.60±2.70③ |
Item | 5-HT concentration/(ng·mL-1) | ||
---|---|---|---|
Control group (n=6) | Model group (n=6) | Model+SA group (n=6) | |
Serum | 234.02±37.52 | 375.38±79.46① | 276.78±45.74③ |
Thoracic aorta | 41.88±3.86 | 19.22±1.56② | 25.31±1.84④ |
Tab 3 Comparison of 5-HT concentration in mice before and after treatment
Item | 5-HT concentration/(ng·mL-1) | ||
---|---|---|---|
Control group (n=6) | Model group (n=6) | Model+SA group (n=6) | |
Serum | 234.02±37.52 | 375.38±79.46① | 276.78±45.74③ |
Thoracic aorta | 41.88±3.86 | 19.22±1.56② | 25.31±1.84④ |
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