›› 2010, Vol. 30 ›› Issue (3): 343-.

• Review • Previous Articles     Next Articles

Mechanisms in heart failure with normal left ventricular ejection fraction caused by hypertension

CAO Li-yuan, SHI Hao-ying, reviewer;DAI Qiu-yan, reviser   

  1. Department of Cardiology, The First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China
  • Online:2010-03-25 Published:2010-03-24

Abstract:

Hypertension is a major contributor to the development of heart failure with normal left ventricular ejection fraction (HFNEF). Generally, hypertensive heart disease is a process of developing ventricular hypertrophy and fibrosis, which eventually leads to diastolic dysfunction and HFNEF. Now little is known about the process from hypertension to HFNEF, and this article explains the mechanisms from three factors of myocardial mechanisms, neuro-endocrinecytokine mechanisms and hemodynamic mechanisms.

Key words: hypertension, heart failure with normal left ventricular ejection fraction, mechanisms