›› 2013, Vol. 33 ›› Issue (1): 109-.doi: 10.3969/j.issn.1674-8115.2013.01.022

• Review • Previous Articles     Next Articles

Research progress of pluripotent stem cells and kidney regeneration

HUANG Jia-hui1, WANG Yang1,2, WANG Gong-xian1   

  1. 1.Institute of Urology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China； 2.Institute of Orthopaedic Trauma, Shanghai Jiaotong University, Shanghai 200233, China
  • Online:2013-01-28 Published:2013-02-06
  • Supported by:

    National Natural Science Foundation of China, 81170640, 30960385

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Abstract:

Although renal transplantation has been proved to be an effective therapeutic strategy for most patients with end-stage renal failure, it is associated with some limitations, including the shortage of donor organs, immune rejection and a lifelong immunosuppressive regimen. Pluripotent stem cells, especially embryonic stem cells and induced pluripotent stem cells, can differentiate into any cell types in the body and show a good prospect of application on tissue and organ regeneration. The research progress of pluripotent stem cells and kidney regeneration is reviewed in this paper.

Key words: pluripotent stem cell, embryonic stem cell, induced pluripotent stem cell, kidney regeneration, cell differentiation