›› 2013, Vol. 33 ›› Issue (2): 253-.doi: 10.3969/j.issn.1674-8115.2013.02.026

• 病例报告 • 上一篇    


郑桂敏1, 王 磊2, 贾秀川2, 张风肖1, 高建霞3   

  1. 1.河北省人民医院风湿免疫科, 石家庄 050051; 2.河北省人民医院医学影像科, 石家庄 050051; 3.军械工程学院门诊部, 石家庄 050003
  • 出版日期:2013-02-28 发布日期:2013-03-07
  • 作者简介:郑桂敏(1976—), 女, 主治医师, 硕士;电子信箱: zhengguimin76@sohu.com。
  • 基金资助:


Three cases report of connective tissue disease complicated with knee joint bone infarction

ZHENG Gui-min1, WANG Lei2, JIA Xiu-chuan2, ZHANG Feng-xiao1, GAO Jian-xia3   

  1. 1.Department of Rheumatology &|Immunology, 2.Department of Medical Imaging, Hebei People´s Hospital, Shijiazhuang 050051, China; 3.Clinic of Ordnance Engineering College, Shijiazhuang 050003, China
  • Online:2013-02-28 Published:2013-03-07
  • Supported by:

    Hebei Province Medical Science Research Foundation, 20090031



关键词: 结缔组织病, 关节炎, 骨梗死


Bone infarction is often found in patients with connective tissue disease due to long-term application of large amount of corticosteroids. For these patients, bone infarction more commonly occurs in hip joints rather than in knee joints. Aching joints and arthritis are routine presentations of connective tissue disease, which may easily result in the misdiagnosis of bone infarction in knee joints. Likewise, bone infarction may hinder the tracking of the development of connective tissue disease. The clinical manifestations, immunological characteristics and course of diagnosis and treatment of 3 cases of connective tissue disease complicated with bone infarction are retrospectively described in this paper. All are females, 2 of whom suffers from systemic lupus erythematosus, and the other Sjogren´s syndrome. All of them are treated with corticosteroids and immunodepressants in a long term, exhibit Raynaud´s phenomenon, and are complicated with multiple or single bone infarction. Management of anti-osteoporosis, blood circulation activation and bone metabolism promotion yields definite effect, and magnetic resonance imaging has a high value in diagnosis. A clinical comprehensive analysis on the basis of symptoms, laboratory results and imaging findings should be carried out to avoid the misdiagnosis.

Key words: connective tissue disease, arthritis, bone infarction