上海交通大学学报(医学版) ›› 2022, Vol. 42 ›› Issue (3): 357-363.doi: 10.3969/j.issn.1674-8115.2022.03.014
收稿日期:
2021-10-15
出版日期:
2022-03-28
发布日期:
2022-05-09
通讯作者:
陆群峰
E-mail:ncdwwll@126.com;luluroom2004@163.com
作者简介:
李燕(1994—),女,护师,硕士;电子信箱:ncdwwll@126.com。
LI Yan1(), JIANG Yan2, KANG Qiongfang3, LU Qunfeng2(
)
Received:
2021-10-15
Online:
2022-03-28
Published:
2022-05-09
Contact:
LU Qunfeng
E-mail:ncdwwll@126.com;luluroom2004@163.com
摘要:
目的·检索、评价和整合预防婴幼儿尿布性皮炎的最佳证据,为减少婴幼儿尿布性皮炎提供循证依据。方法·系统检索BMJ Best Practice、UpToDate、英国国家卫生与临床优化研究所网站、苏格兰校级指南网、加拿大安大略护理学会最佳实践指南、澳大利亚乔安娜布里格斯研究所循证卫生保健中心数据库、Database of Abstracts of Reviews of Effectiveness、Cochrane Library、Campbell协作网、医脉通、PubMed、中国生物医学文献数据库、中华护理学会网站、中华医学会儿科学分会网站中有关预防婴幼儿尿布性皮炎的相关证据,包括临床决策、指南、证据总结、系统评价及专家共识。检索年限为建库至2021年6月。由2名研究者对文献质量进行独立评价,同时提取和汇总相关证据。结果·共纳入8篇文献,包括2篇临床决策、1篇证据总结、4篇系统评价、1篇专家共识。共总结了26条证据,内容包括尿布部位的暴露、屏障制剂的应用、清洁、尿布的选择和更换、教育与培训等方面。结论·临床医护人员应在循证依据的基础上结合文化特点、资源配置和患者特征等情况,优化临床预防尿布性皮炎的流程,重视家庭健康教育,以降低婴幼儿尿布性皮炎发生率。
中图分类号:
李燕, 江艳, 康琼芳, 陆群峰. 婴幼儿尿布性皮炎预防策略的最佳证据总结[J]. 上海交通大学学报(医学版), 2022, 42(3): 357-363.
LI Yan, JIANG Yan, KANG Qiongfang, LU Qunfeng. Summary of the best evidence summary on prevention strategies for diaper dermatitis in infants[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2022, 42(3): 357-363.
Study | Year | Resource | Type | Theme |
---|---|---|---|---|
MATHEW[ | 2021 | JBI | Evidence summary | Management of diaper dermatitis in infants and preschool children |
BAER[ | 2006 | Cochrane | Systematic review | Application of disposable diapers in prevention of infant diaper dermatitis |
DAVIES[ | 2005 | Cochrane | Systematic review | Role of topical vitamin A or its derivatives in the treatment and prevention of infant diaper dermatitis |
ROWE[ | 2008 | JBI | Systematic review | Effect of barrier preparation on prevention/treatment of diaper dermatitis in infants and preschool children |
BLUME-PEYTAVI[ | 2014 | DARE | Systematic review | Prevention of diaper dermatitis in infant: a literature review |
ZHANG[ | 2020 | Medlive | Consensus approach | Expert consensus on nursing practice of infant diaper dermatitis |
HORII[ | 2019 | UptoDate | Clinical decision | Clinical decision making in the management of diaper dermatitis |
BMJ[ | 2018 | Best Practice | Clinical decision | An overview of dermatitis |
表1 纳入文献的一般特征
Tab 1 Characteristics of included studies
Study | Year | Resource | Type | Theme |
---|---|---|---|---|
MATHEW[ | 2021 | JBI | Evidence summary | Management of diaper dermatitis in infants and preschool children |
BAER[ | 2006 | Cochrane | Systematic review | Application of disposable diapers in prevention of infant diaper dermatitis |
DAVIES[ | 2005 | Cochrane | Systematic review | Role of topical vitamin A or its derivatives in the treatment and prevention of infant diaper dermatitis |
ROWE[ | 2008 | JBI | Systematic review | Effect of barrier preparation on prevention/treatment of diaper dermatitis in infants and preschool children |
BLUME-PEYTAVI[ | 2014 | DARE | Systematic review | Prevention of diaper dermatitis in infant: a literature review |
ZHANG[ | 2020 | Medlive | Consensus approach | Expert consensus on nursing practice of infant diaper dermatitis |
HORII[ | 2019 | UptoDate | Clinical decision | Clinical decision making in the management of diaper dermatitis |
BMJ[ | 2018 | Best Practice | Clinical decision | An overview of dermatitis |
Study | Q1 | Q2 | Q3 | Q4 | Q5 | Q6 | Q7 | Q8 | Q9 | Q10 | Q11 | Q12 | Q13 | Q14 | Q15 | Q16 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BAER[ | Y | Y | Y | Y | Y | Y | Y | P | Y | Y | Y | Y | Y | N | Y | Y |
DAVIES[ | Y | Y | Y | Y | Y | Y | P | Y | Y | N | Y | Y | Y | N | Y | Y |
ROWE[ | Y | Y | Y | Y | Y | Y | Y | Y | Y | N | Y | Y | Y | N | Y | Y |
BLUME-PEYTAVI[ | Y | N | Y | Y | Y | N | Y | Y | Y | N | Y | Y | Y | N | N | N |
表2 系统评价的质量评价结果
Tab 2 Quality evaluation of systematic reviews
Study | Q1 | Q2 | Q3 | Q4 | Q5 | Q6 | Q7 | Q8 | Q9 | Q10 | Q11 | Q12 | Q13 | Q14 | Q15 | Q16 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BAER[ | Y | Y | Y | Y | Y | Y | Y | P | Y | Y | Y | Y | Y | N | Y | Y |
DAVIES[ | Y | Y | Y | Y | Y | Y | P | Y | Y | N | Y | Y | Y | N | Y | Y |
ROWE[ | Y | Y | Y | Y | Y | Y | Y | Y | Y | N | Y | Y | Y | N | Y | Y |
BLUME-PEYTAVI[ | Y | N | Y | Y | Y | N | Y | Y | Y | N | Y | Y | Y | N | N | N |
Evaluation criterion | Result | |
---|---|---|
LI[ | ADALAT[ | |
1. Whether the inclusion criteria of the sample are clearly defined | Y | N |
2. Whether the research object and the research site are described in detail | Y | Y |
3. Whether the measurement method of exposure factors has reliability and validity | Y | N/C |
4. Whether diseases or health problems are defined by objective and consistent criteria | Y | Y |
5. Whether confounding factors are identified | N | N |
6. Whether measures are taken to control confounding factors | N | N |
7. Whether the measurement method of outcome index has reliability and validity | Y | Y |
8. Whether the data analysis methods are appropriate | Y | Y |
表3 横断面研究评价结果
Tab 3 Evaluation of cross-sectional studies
Evaluation criterion | Result | |
---|---|---|
LI[ | ADALAT[ | |
1. Whether the inclusion criteria of the sample are clearly defined | Y | N |
2. Whether the research object and the research site are described in detail | Y | Y |
3. Whether the measurement method of exposure factors has reliability and validity | Y | N/C |
4. Whether diseases or health problems are defined by objective and consistent criteria | Y | Y |
5. Whether confounding factors are identified | N | N |
6. Whether measures are taken to control confounding factors | N | N |
7. Whether the measurement method of outcome index has reliability and validity | Y | Y |
8. Whether the data analysis methods are appropriate | Y | Y |
Prevention strategy | Evidence | Grade |
---|---|---|
Air | 1. There should be a period of nappy-free time each day[ | Ⅴb |
Barrier | 2. Apply protectant at each diaper change to protect skin from irritants, such as urine and feces[ | Ⅰc |
3. It is better to choose a barrier preparation or medicine for external usage with the fewest ingredients, avoiding irritating or allergenic ingredients, such as aromatic agent, preservative, neomycin, boric acid, camphor, phenol, benzocaine and salicylate. Otherwise, it may result in systemic toxicity or methemoglobinemia[ | Ⅰc | |
4. Pastes and ointments are usually better than creams and lotions; the adhesion of creams and emulsions is poor and the sealing degree is very low. They often contain aromatics and preservatives as well[ | Ⅰb | |
5. Sucralfate can also act as a physical barrier against irritants. It has antibacterial activity, which is useful in the treatment of severe or intractable irritant diaper dermatitis[ | Ⅳd | |
6. Olive oil and marigold ointment have similar effect on preventing diaper-related dermatitis[ | Ⅰc | |
7. The effect of vitamin A in the prevention of diaper dermatitis is unclear[ | Ⅰc | |
Cleaning | 8. Dry manure can be gently removed by dipping a cotton ball in paraffin oil[ | Ⅴc |
9. Barrier paste doesn’t need to be completely removed at each diaper change, and paraffin oil can be used to assist when necessary[ | Ⅰa | |
10. Excessive use of cleaners and excessive friction should be avoided[ | ||
11. Warm water (37‒40 ℃) and soft cloth can be used to clean the skin, and baby wipes with the least additive and no aromatic agent, ethanol, fluorescent agent, dyes, and preservatives can be chosen. You should scrub and pat gently on the undamaged skin[ | Ⅰa | |
12. Baby wipes should be discontinued if irritation or breakage occurs[ | Ⅴc | |
13. The diaper area should be cleaned with a small amount of a gentle cleanser with a physiological pH[ | Ⅴc | |
14. In preterm and term newborns, the use of wipe will reduce skin pH value, percutaneous moisture loss and less skin erythema[ | Ⅰc | |
15. A separate baby bath should be used to reduce diaper red spots and rough, dry skin[ | Ⅰc | |
16. In the case of bathing twice a week, bathing with water alone can improve newborn skin conditions and reduce the incidence of nappy-related dermatitis compared to bathing with water and body gel[ | Ⅰc | |
Diaper | 17. Disposable diapers are recommended[ | Ⅰa |
18. Nappies with hydroscopicity gel are superior to cellulose core nappies, cellulose core diapers are better than cloth diapers, air permeable nappies are superior to air tight nappies, and diapers with permeability stains are better than regular diapers[ | Ⅰa | |
19. Using plastic underwear over diapers should be avoided[ | Ⅴc | |
20. Diapers should at suitable size and tightness[ | Ⅴb | |
21. If the baby is allergic to diapers, a different brand or a soft cotton diaper should be chosen[ | Ⅴb | |
22. Frequent diaper changes are effective measures to prevent diaper dermatitis[ | Ⅰa | |
23. Diapers should be changed every 2 h (or checked for soiled at least every 2 h), and newborns and children with diarrhea should be changed more frequently [ | Ⅴb | |
24. Diapers after defecation immediately should be changed[ | Ⅴb | |
25. The diaper should be replaced 1 h after diuretic application[ | Ⅴb | |
Education | 26. Parents and healthcare personnel should be educated on appropriate exposure, selection of barrier agents, skin cleaning, diaper selection, and timing of diaper change[ | Ⅴb |
表4 婴幼儿尿布性皮炎风险筛查和预防策略的最佳证据总结
Tab 4 Summary of the best evidence on risk screening and prevention strategies for diaper dermatitis in infants
Prevention strategy | Evidence | Grade |
---|---|---|
Air | 1. There should be a period of nappy-free time each day[ | Ⅴb |
Barrier | 2. Apply protectant at each diaper change to protect skin from irritants, such as urine and feces[ | Ⅰc |
3. It is better to choose a barrier preparation or medicine for external usage with the fewest ingredients, avoiding irritating or allergenic ingredients, such as aromatic agent, preservative, neomycin, boric acid, camphor, phenol, benzocaine and salicylate. Otherwise, it may result in systemic toxicity or methemoglobinemia[ | Ⅰc | |
4. Pastes and ointments are usually better than creams and lotions; the adhesion of creams and emulsions is poor and the sealing degree is very low. They often contain aromatics and preservatives as well[ | Ⅰb | |
5. Sucralfate can also act as a physical barrier against irritants. It has antibacterial activity, which is useful in the treatment of severe or intractable irritant diaper dermatitis[ | Ⅳd | |
6. Olive oil and marigold ointment have similar effect on preventing diaper-related dermatitis[ | Ⅰc | |
7. The effect of vitamin A in the prevention of diaper dermatitis is unclear[ | Ⅰc | |
Cleaning | 8. Dry manure can be gently removed by dipping a cotton ball in paraffin oil[ | Ⅴc |
9. Barrier paste doesn’t need to be completely removed at each diaper change, and paraffin oil can be used to assist when necessary[ | Ⅰa | |
10. Excessive use of cleaners and excessive friction should be avoided[ | ||
11. Warm water (37‒40 ℃) and soft cloth can be used to clean the skin, and baby wipes with the least additive and no aromatic agent, ethanol, fluorescent agent, dyes, and preservatives can be chosen. You should scrub and pat gently on the undamaged skin[ | Ⅰa | |
12. Baby wipes should be discontinued if irritation or breakage occurs[ | Ⅴc | |
13. The diaper area should be cleaned with a small amount of a gentle cleanser with a physiological pH[ | Ⅴc | |
14. In preterm and term newborns, the use of wipe will reduce skin pH value, percutaneous moisture loss and less skin erythema[ | Ⅰc | |
15. A separate baby bath should be used to reduce diaper red spots and rough, dry skin[ | Ⅰc | |
16. In the case of bathing twice a week, bathing with water alone can improve newborn skin conditions and reduce the incidence of nappy-related dermatitis compared to bathing with water and body gel[ | Ⅰc | |
Diaper | 17. Disposable diapers are recommended[ | Ⅰa |
18. Nappies with hydroscopicity gel are superior to cellulose core nappies, cellulose core diapers are better than cloth diapers, air permeable nappies are superior to air tight nappies, and diapers with permeability stains are better than regular diapers[ | Ⅰa | |
19. Using plastic underwear over diapers should be avoided[ | Ⅴc | |
20. Diapers should at suitable size and tightness[ | Ⅴb | |
21. If the baby is allergic to diapers, a different brand or a soft cotton diaper should be chosen[ | Ⅴb | |
22. Frequent diaper changes are effective measures to prevent diaper dermatitis[ | Ⅰa | |
23. Diapers should be changed every 2 h (or checked for soiled at least every 2 h), and newborns and children with diarrhea should be changed more frequently [ | Ⅴb | |
24. Diapers after defecation immediately should be changed[ | Ⅴb | |
25. The diaper should be replaced 1 h after diuretic application[ | Ⅴb | |
Education | 26. Parents and healthcare personnel should be educated on appropriate exposure, selection of barrier agents, skin cleaning, diaper selection, and timing of diaper change[ | Ⅴb |
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